TY - JOUR
T1 - Sex-specific clinical correlates of hoarding in obsessive-compulsive disorder
AU - Samuels, Jack F.
AU - Bienvenu, O. Joseph
AU - Pinto, Anthony
AU - Murphy, Dennis L.
AU - Piacentini, John
AU - Rauch, Scott L.
AU - Fyer, Abby J.
AU - Grados, Marco A.
AU - Greenberg, Benjamin D.
AU - Knowles, James A.
AU - McCracken, James T.
AU - Cullen, Bernadette
AU - Riddle, Mark A.
AU - Rasmussen, Steven A.
AU - Pauls, David L.
AU - Liang, Kung Yee
AU - Hoehn-Saric, Rudolf
AU - Pulver, Ann E.
AU - Nestadt, Gerald
N1 - Funding Information:
This research was supported by National Institute of Health grants R01 MH50214, RO1 MH071507, K23-MH64543, and NIH/NCRR/OPD-GCRC RR00052.
PY - 2008/9
Y1 - 2008/9
N2 - Little is known about whether the clinical correlates of hoarding behavior are different in men and women with obsessive-compulsive disorder (OCD). In the current study, we evaluated the association of hoarding with categories of obsessions and compulsions, psychiatric disorders, personality dimensions, and other clinical characteristics separately in 151 men and 358 women with OCD who were examined during the OCD Collaborative Genetics Study. We found that, among men but not women, hoarding was associated with aggressive, sexual, and religious obsessions and checking compulsions. In men, hoarding was associated with generalized anxiety disorder and tics whereas, among women, hoarding was associated with social phobia, post-traumatic stress disorder, body dysmorphic disorder, nail biting, and skin picking. In women but not men, hoarding was associated with schizotypal and dependent personality disorder dimensions, and with low conscientiousness. These findings indicate that specific clinical correlates of hoarding in OCD are different in men and women and may reflect sex-specific differences in the course, expression, and/or etiology of hoarding behavior in OCD.
AB - Little is known about whether the clinical correlates of hoarding behavior are different in men and women with obsessive-compulsive disorder (OCD). In the current study, we evaluated the association of hoarding with categories of obsessions and compulsions, psychiatric disorders, personality dimensions, and other clinical characteristics separately in 151 men and 358 women with OCD who were examined during the OCD Collaborative Genetics Study. We found that, among men but not women, hoarding was associated with aggressive, sexual, and religious obsessions and checking compulsions. In men, hoarding was associated with generalized anxiety disorder and tics whereas, among women, hoarding was associated with social phobia, post-traumatic stress disorder, body dysmorphic disorder, nail biting, and skin picking. In women but not men, hoarding was associated with schizotypal and dependent personality disorder dimensions, and with low conscientiousness. These findings indicate that specific clinical correlates of hoarding in OCD are different in men and women and may reflect sex-specific differences in the course, expression, and/or etiology of hoarding behavior in OCD.
KW - Comorbidity
KW - Hoarding
KW - Obsessive-compulsive disorder
KW - Personality
KW - Personality disorders
KW - Sex differences
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U2 - 10.1016/j.brat.2008.06.005
DO - 10.1016/j.brat.2008.06.005
M3 - Article
C2 - 18692168
AN - SCOPUS:50449083286
SN - 0005-7967
VL - 46
SP - 1040
EP - 1046
JO - Behaviour Research and Therapy
JF - Behaviour Research and Therapy
IS - 9
ER -