Sex, lies, and gastrointestinal tract biopsies: A review of selected sexually transmitted proctocolitides

Lysandra Voltaggio, Elizabeth A Montgomery, M. Aamir Ali, Aatur D. Singhi, Christina A. Arnold

Research output: Contribution to journalArticle

Abstract

There are many insults that result in gastrointestinal tract inflammation. Infections can be particularly challenging because (1) only a limited number of organisms provoke a specific endoscopic and/or histologic appearance; and (2) although some organisms may be present on biopsies, the findings may be so subtle or organisms so few that they are easily missed if the reviewer is not performing a specific search for the offender. Sexually transmitted infections (STI) are rarely a consideration at the time of GI biopsy examination and clinicians rarely inquire about sexual behavior at the time of initial patient interview. Although establishing a definitive STI diagnosis is not possible on histology alone, these infections are associated with inflammatory patterns that may help raise this diagnostic possibility. Becoming familiar with these patterns is necessary as worldwide outbreaks of these infections are being reported. This review aims to provide the pathologist with histologic clues associated with the most frequently encountered bacterial pathogens in the setting of STI proctitis, namely, Chlamydia trachomatis, Neisseria gonorrhoeae, and Treponema pallidum.

Original languageEnglish (US)
Pages (from-to)83-93
Number of pages11
JournalAdvances in Anatomic Pathology
Volume21
Issue number2
DOIs
StatePublished - 2014
Externally publishedYes

Fingerprint

Proctocolitis
Sexually Transmitted Diseases
Gastrointestinal Tract
Biopsy
Infection
Proctitis
Treponema pallidum
Neisseria gonorrhoeae
Chlamydia trachomatis
Sexual Behavior
Disease Outbreaks
Histology
Interviews
Inflammation

Keywords

  • Chlamydia
  • Colitis
  • Gonorrhea
  • Inflammatory bowel disease
  • Sexually transmitted
  • Syphilis

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Anatomy

Cite this

Sex, lies, and gastrointestinal tract biopsies : A review of selected sexually transmitted proctocolitides. / Voltaggio, Lysandra; Montgomery, Elizabeth A; Ali, M. Aamir; Singhi, Aatur D.; Arnold, Christina A.

In: Advances in Anatomic Pathology, Vol. 21, No. 2, 2014, p. 83-93.

Research output: Contribution to journalArticle

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