Sex, drugs, and cognition: effects of marijuana.

Beth M. Anderson, Matthew Rizzo, Robert I. Block, Godfrey D. Pearlson, Daniel S. O'Leary

Research output: Contribution to journalArticle

Abstract

Despite the knowledge that many drugs affect men and women differently, few studies exploring the effects of marijuana use on cognition have included women. Findings from both animal and human studies suggest marijuana may have more marked effects in women. This study examined sex differences in the acute effects of marijuana on cognition in 70 (n=35 male, 35 female) occasional users of marijuana. Tasks were chosen to tap a wide variety of cognitive domains affected by sex and/or marijuana including attention, cognitive flexibility, time estimation, and visuospatial processing. As expected, acute marijuana use impaired performance on selective and divided attention, time estimation, and cognitive flexibility. While there did not appear to be sex differences in marijuana's effects on cognition, women requested to discontinue the smoking session more often than men, likely leading to an underestimation of differences. Further study of psychological differences in marijuana's effects on men and women following both acute and residual effects of marijuana is warranted.

Original languageEnglish (US)
Pages (from-to)413-424
Number of pages12
JournalJournal of Psychoactive Drugs
Volume42
Issue number4
StatePublished - Dec 2010
Externally publishedYes

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Cannabis
Cognition
Pharmaceutical Preparations
Sex Characteristics
Smoking
Psychology

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Psychology(all)

Cite this

Anderson, B. M., Rizzo, M., Block, R. I., Pearlson, G. D., & O'Leary, D. S. (2010). Sex, drugs, and cognition: effects of marijuana. Journal of Psychoactive Drugs, 42(4), 413-424.

Sex, drugs, and cognition : effects of marijuana. / Anderson, Beth M.; Rizzo, Matthew; Block, Robert I.; Pearlson, Godfrey D.; O'Leary, Daniel S.

In: Journal of Psychoactive Drugs, Vol. 42, No. 4, 12.2010, p. 413-424.

Research output: Contribution to journalArticle

Anderson, BM, Rizzo, M, Block, RI, Pearlson, GD & O'Leary, DS 2010, 'Sex, drugs, and cognition: effects of marijuana.', Journal of Psychoactive Drugs, vol. 42, no. 4, pp. 413-424.
Anderson BM, Rizzo M, Block RI, Pearlson GD, O'Leary DS. Sex, drugs, and cognition: effects of marijuana. Journal of Psychoactive Drugs. 2010 Dec;42(4):413-424.
Anderson, Beth M. ; Rizzo, Matthew ; Block, Robert I. ; Pearlson, Godfrey D. ; O'Leary, Daniel S. / Sex, drugs, and cognition : effects of marijuana. In: Journal of Psychoactive Drugs. 2010 ; Vol. 42, No. 4. pp. 413-424.
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