TY - JOUR
T1 - Sex differences in the inferior parietal lobule
AU - Frederikse, Melissa E.
AU - Lu, Angela
AU - Aylward, Elizabeth
AU - Barta, Patrick
AU - Pearlson, Godfrey
PY - 1999
Y1 - 1999
N2 - The inferior parietal lobule (IPL) - a neocortical region and part of the heteromodal association cortex (HASC) - has been hypothesized to exhibit sexual dimorphism, as do other HASC regions, particularly with regard to asymmetry. Using a reliable method for measuring IPL gray matter volume based upon individual sulcal-gyral landmarks, we measured this region on magnetic resonance imaging scans from a sample of 15 individually matched pairs of normal male and female subjects. Male subjects showed significantly larger left, but not right, IPL volumes when compared to females. Males also showed a leftward (left > right) asymmetry for the IPL, with a less marked opposite asymmetry in females. Such sexual dimorphisms may possibly underlie the subtle cognitive differences observed between the sexes.
AB - The inferior parietal lobule (IPL) - a neocortical region and part of the heteromodal association cortex (HASC) - has been hypothesized to exhibit sexual dimorphism, as do other HASC regions, particularly with regard to asymmetry. Using a reliable method for measuring IPL gray matter volume based upon individual sulcal-gyral landmarks, we measured this region on magnetic resonance imaging scans from a sample of 15 individually matched pairs of normal male and female subjects. Male subjects showed significantly larger left, but not right, IPL volumes when compared to females. Males also showed a leftward (left > right) asymmetry for the IPL, with a less marked opposite asymmetry in females. Such sexual dimorphisms may possibly underlie the subtle cognitive differences observed between the sexes.
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U2 - 10.1093/cercor/9.8.896
DO - 10.1093/cercor/9.8.896
M3 - Article
C2 - 10601007
AN - SCOPUS:0033452669
SN - 1047-3211
VL - 9
SP - 896
EP - 901
JO - Cerebral Cortex
JF - Cerebral Cortex
IS - 8
ER -