Sex differences in cerebral laterality of language and visuospatial processing

A. M. Clements, S. L. Rimrodt, J. R. Abel, J. G. Blankner, Stewart H Mostofsky, James J Pekar, Martha Bridge Denckla, L. E. Cutting

Research output: Contribution to journalArticle

Abstract

Sex differences on language and visuospatial tasks are of great interest, with differences in hemispheric laterality hypothesized to exist between males and females. Some functional imaging studies examining sex differences have shown that males are more left lateralized on language tasks and females are more right lateralized on visuospatial tasks; however, findings are inconsistent. Here we used functional magnetic resonance imaging to study thirty participants, matched on task performance, during phonological and visuospatial tasks. For each task, region-of-interest analyses were used to test differences in cerebral laterality. Results indicate that lateralization differences exist, with males more left lateralized during the phonological task and showing greater bilateral activity during the visuospatial task, whereas females showed greater bilateral activity during the phonological task and were more right lateralized during the visuospatial task. Our data provide clear evidence for differences in laterality between males and females when processing language versus visuospatial information.

Original languageEnglish (US)
Pages (from-to)150-158
Number of pages9
JournalBrain and Language
Volume98
Issue number2
DOIs
StatePublished - Aug 2006

Fingerprint

Sex Characteristics
Language
language
Task Performance and Analysis
performance
evidence
Magnetic Resonance Imaging
Laterality
Sex Differences

Keywords

  • Gender
  • Language
  • Neuroimaging
  • Sex differences
  • Visuospatial processing

ASJC Scopus subject areas

  • Language and Linguistics
  • Experimental and Cognitive Psychology
  • Neuropsychology and Physiological Psychology
  • Neuroscience(all)

Cite this

Sex differences in cerebral laterality of language and visuospatial processing. / Clements, A. M.; Rimrodt, S. L.; Abel, J. R.; Blankner, J. G.; Mostofsky, Stewart H; Pekar, James J; Denckla, Martha Bridge; Cutting, L. E.

In: Brain and Language, Vol. 98, No. 2, 08.2006, p. 150-158.

Research output: Contribution to journalArticle

Clements, A. M. ; Rimrodt, S. L. ; Abel, J. R. ; Blankner, J. G. ; Mostofsky, Stewart H ; Pekar, James J ; Denckla, Martha Bridge ; Cutting, L. E. / Sex differences in cerebral laterality of language and visuospatial processing. In: Brain and Language. 2006 ; Vol. 98, No. 2. pp. 150-158.
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