Sex-biased Immune Responses Following SARS-CoV-2 Infection

Rebecca L. Ursin; Janna R. Shapiro; Sabra L. Klein

doi:10.1016/j.tim.2020.10.002

Sex-biased Immune Responses Following SARS-CoV-2 Infection

Rebecca L. Ursin, Janna R. Shapiro, Sabra L. Klein

Bloomberg School of Public Health

Research output: Contribution to journal › Short survey › peer-review

1 Scopus citations

Abstract

Males are disproportionately affected by severe disease and death from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In their recent article, Takahashi et al. found sex differences in immune responses to SARS-CoV-2 and the predictors of disease progression. These findings contribute to elucidating the mechanisms that underlie the male bias in severe disease and death from coronavirus disease 2019 (COVID-19).

Original language	English (US)
Pages (from-to)	952-954
Number of pages	3
Journal	Trends in Microbiology
Volume	28
Issue number	12
DOIs	https://doi.org/10.1016/j.tim.2020.10.002
State	Published - Dec 2020

Keywords

COVID-19
SARS-CoV-2
biological sex
immunopathogenesis

ASJC Scopus subject areas

Microbiology
Microbiology (medical)
Infectious Diseases
Virology

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10.1016/j.tim.2020.10.002

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title = "Sex-biased Immune Responses Following SARS-CoV-2 Infection",

abstract = "Males are disproportionately affected by severe disease and death from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In their recent article, Takahashi et al. found sex differences in immune responses to SARS-CoV-2 and the predictors of disease progression. These findings contribute to elucidating the mechanisms that underlie the male bias in severe disease and death from coronavirus disease 2019 (COVID-19).",

keywords = "COVID-19, SARS-CoV-2, biological sex, immunopathogenesis",

author = "Ursin, {Rebecca L.} and Shapiro, {Janna R.} and Klein, {Sabra L.}",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier Ltd",

year = "2020",

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doi = "10.1016/j.tim.2020.10.002",

language = "English (US)",

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AU - Ursin, Rebecca L.

AU - Shapiro, Janna R.

AU - Klein, Sabra L.

PY - 2020/12

Y1 - 2020/12

N2 - Males are disproportionately affected by severe disease and death from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In their recent article, Takahashi et al. found sex differences in immune responses to SARS-CoV-2 and the predictors of disease progression. These findings contribute to elucidating the mechanisms that underlie the male bias in severe disease and death from coronavirus disease 2019 (COVID-19).

AB - Males are disproportionately affected by severe disease and death from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In their recent article, Takahashi et al. found sex differences in immune responses to SARS-CoV-2 and the predictors of disease progression. These findings contribute to elucidating the mechanisms that underlie the male bias in severe disease and death from coronavirus disease 2019 (COVID-19).

KW - COVID-19

KW - SARS-CoV-2

KW - biological sex

KW - immunopathogenesis

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JO - Trends in Microbiology

JF - Trends in Microbiology

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ER -

Sex-biased Immune Responses Following SARS-CoV-2 Infection

Abstract

Keywords

ASJC Scopus subject areas

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