Sex-biased Immune Responses Following SARS-CoV-2 Infection

Rebecca L. Ursin, Janna R. Shapiro, Sabra L. Klein

Research output: Contribution to journalShort surveypeer-review


Males are disproportionately affected by severe disease and death from severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. In their recent article, Takahashi et al. found sex differences in immune responses to SARS-CoV-2 and the predictors of disease progression. These findings contribute to elucidating the mechanisms that underlie the male bias in severe disease and death from coronavirus disease 2019 (COVID-19).

Original languageEnglish (US)
Pages (from-to)952-954
Number of pages3
JournalTrends in Microbiology
Issue number12
StatePublished - Dec 2020


  • COVID-19
  • SARS-CoV-2
  • biological sex
  • immunopathogenesis

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)
  • Infectious Diseases
  • Virology


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