Sex and gender impact immune responses to vaccines among the elderly

Ashley L. Fink, Sabra L Klein

Research output: Contribution to journalArticle

Abstract

In response to the recommended vaccines in older-aged individuals, sex differences occur in response to those that protect against influenza, tetanus, pertussis, shingles, and pneumococcal infections. The efficacy of vaccines recommended for older-aged adults is consistently greater for females than for males. Gender differences as well as biological sex differences can influence vaccine uptake, responses, and outcome in older-aged individuals, which should influence guidelines, formulations, and dosage recommendations for vaccines in the elderly.

Original languageEnglish (US)
Pages (from-to)408-416
Number of pages9
JournalPhysiology
Volume30
Issue number6
DOIs
StatePublished - Nov 1 2015

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Vaccines
Sex Characteristics
Pneumococcal Infections
Whooping Cough
Tetanus
Herpes Zoster
Individuality
Human Influenza
Guidelines

ASJC Scopus subject areas

  • Physiology

Cite this

Sex and gender impact immune responses to vaccines among the elderly. / Fink, Ashley L.; Klein, Sabra L.

In: Physiology, Vol. 30, No. 6, 01.11.2015, p. 408-416.

Research output: Contribution to journalArticle

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