Sex and gender impact immune responses to vaccines among the elderly

Ashley L. Fink, Sabra L. Klein

Research output: Contribution to journalReview article

Abstract

In response to the recommended vaccines in older-aged individuals, sex differences occur in response to those that protect against influenza, tetanus, pertussis, shingles, and pneumococcal infections. The efficacy of vaccines recommended for older-aged adults is consistently greater for females than for males. Gender differences as well as biological sex differences can influence vaccine uptake, responses, and outcome in older-aged individuals, which should influence guidelines, formulations, and dosage recommendations for vaccines in the elderly.

Original languageEnglish (US)
Pages (from-to)408-416
Number of pages9
JournalPhysiology
Volume30
Issue number6
DOIs
StatePublished - Nov 1 2015

ASJC Scopus subject areas

  • Physiology

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