Sex and age differences in the associations between sleep behaviors and all-cause mortality in older adults: results from the National Health and Nutrition Examination Surveys

Hind A. Beydoun, May A. Beydoun, Xiaoli Chen, Jen Jen Chang, Alyssa A. Gamaldo, Shaker M Eid, Alan B. Zonderman

Research output: Contribution to journalArticle

Abstract

Objective Our aim was to examine sex- and age-specific relationships of sleep behaviors with all-cause mortality rates. Methods A retrospective cohort study was conducted among 5288 adults (≥50 years) from the 2005–2008 National Health and Nutrition Examination Surveys who were followed-up for 54.9 ± 1.2 months. Sleep duration was categorized as < 7 h, 7–8 h and >8 h. Two sleep quality indices were generated through factor analyses. ‘Help-seeking behavior for sleep problems’ and ‘diagnosis with sleep disorders’ were defined as yes/no questions. Sociodemographic covariates-adjusted Cox regression models were applied to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). Results A positive relationship was observed between long sleep and all-cause mortality rate in the overall sample (HR = 1.90, 95% CI: 1.38, 2.60), among males (HR = 1.48, 95% CI: 1.05, 2.09), females (HR = 2.32, 95% CI: 1.48, 3.61) and elderly (≥65 years) people (HR = 1.80, 95% CI: 1.30, 2.50). ‘Sleepiness/sleep disturbance’ (Factor I) and all-cause mortality rate were positively associated among males (HR = 1.22, 95% CI: 1.03, 1.45), whereas ‘poor sleep-related daytime dysfunction’ (Factor II) and all-cause mortality (HR = 0.75, 95% CI: 0.62, 0.91) were negatively associated among elderly people. Conclusions Sex- and age-specific relationships were observed between all-cause mortality rate and specific sleep behaviors among older adults.

Original languageEnglish (US)
Pages (from-to)141-151
Number of pages11
JournalSleep Medicine
Volume36
DOIs
StatePublished - Aug 1 2017

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Nutrition Surveys
Sex Characteristics
Sleep
Confidence Intervals
Mortality
Proportional Hazards Models
Statistical Factor Analysis
Cohort Studies
Retrospective Studies

Keywords

  • Age
  • Cohort study
  • Mortality
  • Sex
  • Sleep
  • Surveillance

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Sex and age differences in the associations between sleep behaviors and all-cause mortality in older adults : results from the National Health and Nutrition Examination Surveys. / Beydoun, Hind A.; Beydoun, May A.; Chen, Xiaoli; Chang, Jen Jen; Gamaldo, Alyssa A.; Eid, Shaker M; Zonderman, Alan B.

In: Sleep Medicine, Vol. 36, 01.08.2017, p. 141-151.

Research output: Contribution to journalArticle

Beydoun, Hind A. ; Beydoun, May A. ; Chen, Xiaoli ; Chang, Jen Jen ; Gamaldo, Alyssa A. ; Eid, Shaker M ; Zonderman, Alan B. / Sex and age differences in the associations between sleep behaviors and all-cause mortality in older adults : results from the National Health and Nutrition Examination Surveys. In: Sleep Medicine. 2017 ; Vol. 36. pp. 141-151.
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abstract = "Objective Our aim was to examine sex- and age-specific relationships of sleep behaviors with all-cause mortality rates. Methods A retrospective cohort study was conducted among 5288 adults (≥50 years) from the 2005–2008 National Health and Nutrition Examination Surveys who were followed-up for 54.9 ± 1.2 months. Sleep duration was categorized as < 7 h, 7–8 h and >8 h. Two sleep quality indices were generated through factor analyses. ‘Help-seeking behavior for sleep problems’ and ‘diagnosis with sleep disorders’ were defined as yes/no questions. Sociodemographic covariates-adjusted Cox regression models were applied to estimate hazard ratios (HRs) and 95{\%} confidence intervals (CIs). Results A positive relationship was observed between long sleep and all-cause mortality rate in the overall sample (HR = 1.90, 95{\%} CI: 1.38, 2.60), among males (HR = 1.48, 95{\%} CI: 1.05, 2.09), females (HR = 2.32, 95{\%} CI: 1.48, 3.61) and elderly (≥65 years) people (HR = 1.80, 95{\%} CI: 1.30, 2.50). ‘Sleepiness/sleep disturbance’ (Factor I) and all-cause mortality rate were positively associated among males (HR = 1.22, 95{\%} CI: 1.03, 1.45), whereas ‘poor sleep-related daytime dysfunction’ (Factor II) and all-cause mortality (HR = 0.75, 95{\%} CI: 0.62, 0.91) were negatively associated among elderly people. Conclusions Sex- and age-specific relationships were observed between all-cause mortality rate and specific sleep behaviors among older adults.",
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T1 - Sex and age differences in the associations between sleep behaviors and all-cause mortality in older adults

T2 - results from the National Health and Nutrition Examination Surveys

AU - Beydoun, Hind A.

AU - Beydoun, May A.

AU - Chen, Xiaoli

AU - Chang, Jen Jen

AU - Gamaldo, Alyssa A.

AU - Eid, Shaker M

AU - Zonderman, Alan B.

PY - 2017/8/1

Y1 - 2017/8/1

N2 - Objective Our aim was to examine sex- and age-specific relationships of sleep behaviors with all-cause mortality rates. Methods A retrospective cohort study was conducted among 5288 adults (≥50 years) from the 2005–2008 National Health and Nutrition Examination Surveys who were followed-up for 54.9 ± 1.2 months. Sleep duration was categorized as < 7 h, 7–8 h and >8 h. Two sleep quality indices were generated through factor analyses. ‘Help-seeking behavior for sleep problems’ and ‘diagnosis with sleep disorders’ were defined as yes/no questions. Sociodemographic covariates-adjusted Cox regression models were applied to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). Results A positive relationship was observed between long sleep and all-cause mortality rate in the overall sample (HR = 1.90, 95% CI: 1.38, 2.60), among males (HR = 1.48, 95% CI: 1.05, 2.09), females (HR = 2.32, 95% CI: 1.48, 3.61) and elderly (≥65 years) people (HR = 1.80, 95% CI: 1.30, 2.50). ‘Sleepiness/sleep disturbance’ (Factor I) and all-cause mortality rate were positively associated among males (HR = 1.22, 95% CI: 1.03, 1.45), whereas ‘poor sleep-related daytime dysfunction’ (Factor II) and all-cause mortality (HR = 0.75, 95% CI: 0.62, 0.91) were negatively associated among elderly people. Conclusions Sex- and age-specific relationships were observed between all-cause mortality rate and specific sleep behaviors among older adults.

AB - Objective Our aim was to examine sex- and age-specific relationships of sleep behaviors with all-cause mortality rates. Methods A retrospective cohort study was conducted among 5288 adults (≥50 years) from the 2005–2008 National Health and Nutrition Examination Surveys who were followed-up for 54.9 ± 1.2 months. Sleep duration was categorized as < 7 h, 7–8 h and >8 h. Two sleep quality indices were generated through factor analyses. ‘Help-seeking behavior for sleep problems’ and ‘diagnosis with sleep disorders’ were defined as yes/no questions. Sociodemographic covariates-adjusted Cox regression models were applied to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). Results A positive relationship was observed between long sleep and all-cause mortality rate in the overall sample (HR = 1.90, 95% CI: 1.38, 2.60), among males (HR = 1.48, 95% CI: 1.05, 2.09), females (HR = 2.32, 95% CI: 1.48, 3.61) and elderly (≥65 years) people (HR = 1.80, 95% CI: 1.30, 2.50). ‘Sleepiness/sleep disturbance’ (Factor I) and all-cause mortality rate were positively associated among males (HR = 1.22, 95% CI: 1.03, 1.45), whereas ‘poor sleep-related daytime dysfunction’ (Factor II) and all-cause mortality (HR = 0.75, 95% CI: 0.62, 0.91) were negatively associated among elderly people. Conclusions Sex- and age-specific relationships were observed between all-cause mortality rate and specific sleep behaviors among older adults.

KW - Age

KW - Cohort study

KW - Mortality

KW - Sex

KW - Sleep

KW - Surveillance

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