Seventeen Y-chromosomal short tandem repeat haplotypes in seven groups of population living in Taiwan

Hsiao Lin Hwa, Li Hui Tseng, Tsang Ming Ko, Yih Yuan Chang, Hsiang Yi Yin, Yi Ning Su, James Chun I Lee

Research output: Contribution to journalArticlepeer-review

Abstract

The analysis of Y-chromosome short tandem repeat (Y-STR) loci is a powerful tool in forensic casework. The aim of this study was to present the 17 Y-STR loci haplotype distributions of groups of population living in Taiwan and to demonstrate genetic distances between the groups as well as multidimensional scaling plot based on Y-STR genotype data. Five hundred and fifteen DNA samples from unrelated males of seven groups of population, including Taiwanese Han, two groups of indigenous Taiwanese of Taiwan Island, Tao, mainland Chinese, Filipinos, and a group of people with European, Near Eastern, or South Asian ancestry, were analyzed using a commercial kit that co-amplifies 17 Y-STRs. A total of 471 different haplotypes with 440 unique haplotypes were identified. The overall haplotype diversity was 0.9995∈±∈0.0002. High haplotype diversity was observed in six groups of population, except the Tao. These Y-STRs revealed a low discrimination capacity in the Tao population (36.84%), which should be considered in forensic practice. The multidimensional scaling plot of these seven groups of population constructed based on the genetic distances according to 17 Y-STR loci presented a clear patrilineal genetic substructure in the area. Partial Y-STRs profiling reduced the discrimination capacity in most groups of population and distorted the multidimensional scaling plot.

Original languageEnglish (US)
Pages (from-to)295-300
Number of pages6
JournalInternational Journal of Legal Medicine
Volume124
Issue number4
DOIs
StatePublished - Jul 2010
Externally publishedYes

Keywords

  • Forensic genetics
  • Multidimensional scaling plot
  • Short tandem repeats
  • Y-chromosome

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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