Serum potassium and the racial disparity in diabetes risk

The Atherosclerosis Risk in Communities (ARIC) Study1-4

Ranee Chatterjee, Hsin Chieh Yeh, Tariq Shafi, Cheryl Anderson, James S. Pankow, Edgar R Miller, David Levine, Elizabeth Selvin, Frederick L. Brancati

Research output: Contribution to journalArticle

Abstract

Background: Low serum potassium appears to be independently associated with incident type 2 diabetes, and low dietary potassium is more common in African Americans than in whites. Objective: We hypothesized that low serum potassium contributes to the excess risk of diabetes in African Americans. Design: We analyzed data collected from 1987 to 1996 from the Atherosclerosis Risk in Communities (ARIC) Study. At baseline, we identified 2716 African American and 9493 white participants without diabetes. We used multivariate Cox models to estimate the relative hazards (RHs) of incident diabetes related to baseline serum potassium during 9 y of follow-up. Results: Mean serum potassium concentrations were lower in African Americans than in whites at baseline (4.2 compared with 4.5 mEq/L; P <0.01), and African Americans had a greater incidence of diabetes than did whites (26 compared with 13 cases/1000 person-years). The adjusted RHs (95% CI) of incident diabetes for those with serum potassium concentrations of

Original languageEnglish (US)
Pages (from-to)1087-1091
Number of pages5
JournalAmerican Journal of Clinical Nutrition
Volume93
Issue number5
DOIs
StatePublished - May 1 2011

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African Americans
Atherosclerosis
Potassium
Serum
Dietary Potassium
Proportional Hazards Models
Type 2 Diabetes Mellitus
Incidence

ASJC Scopus subject areas

  • Medicine (miscellaneous)
  • Nutrition and Dietetics

Cite this

Serum potassium and the racial disparity in diabetes risk : The Atherosclerosis Risk in Communities (ARIC) Study1-4. / Chatterjee, Ranee; Yeh, Hsin Chieh; Shafi, Tariq; Anderson, Cheryl; Pankow, James S.; Miller, Edgar R; Levine, David; Selvin, Elizabeth; Brancati, Frederick L.

In: American Journal of Clinical Nutrition, Vol. 93, No. 5, 01.05.2011, p. 1087-1091.

Research output: Contribution to journalArticle

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