Serum concentrations of steroids, parathyroid hormone, and calcitonin in postmenopausal women during the year following hip fracture: Effect of location of fracture and age

Norman H. Dubin, Lauren K. Monahan, Janet A. Yu-Yahiro, Roger H. Michael, Sheryl I. Zimmerman, William Hawkes, J. Richard Hebel, Kathleen M. Fox, Jay Magaziner

Research output: Contribution to journalArticle

Abstract

Background. Hip fracture in the aged is a major health problem, especially considering the increasing proportion of the elderly in the population. This study examines changes in circulating levels of hormones, which are purported to affect bone metabolism, in response to hip fracture in postmenopausal women. Methods. Patients consisted of women ages 65 and older who had surgery within 2 days of fracture. Serum samples were obtained at 3, 10, 60, 180, and 360 days postfracture. Healthy women without hip fractures from the same age range served as a control group (n=17). Hormones were determined by radioimmunoassay. Subjects with fractures in the neck region of the femur (n=78) were compared to subjects with fractures in the trochanteric region (n=88). Results. Estrone concentration (47.6 ± 5.7 pg/mL; mean ± SEM) at 3 days postfracture was elevated (p

Original languageEnglish (US)
JournalJournals of Gerontology - Series A Biological Sciences and Medical Sciences
Volume54
Issue number9
StatePublished - Sep 1999
Externally publishedYes

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Hip Fractures
Calcitonin
Parathyroid Hormone
Steroids
Serum
Hormones
Estrone
Femur Neck
Radioimmunoassay
Bone and Bones
Control Groups
Health
Population

ASJC Scopus subject areas

  • Aging

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Serum concentrations of steroids, parathyroid hormone, and calcitonin in postmenopausal women during the year following hip fracture : Effect of location of fracture and age. / Dubin, Norman H.; Monahan, Lauren K.; Yu-Yahiro, Janet A.; Michael, Roger H.; Zimmerman, Sheryl I.; Hawkes, William; Hebel, J. Richard; Fox, Kathleen M.; Magaziner, Jay.

In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences, Vol. 54, No. 9, 09.1999.

Research output: Contribution to journalArticle

Dubin, Norman H. ; Monahan, Lauren K. ; Yu-Yahiro, Janet A. ; Michael, Roger H. ; Zimmerman, Sheryl I. ; Hawkes, William ; Hebel, J. Richard ; Fox, Kathleen M. ; Magaziner, Jay. / Serum concentrations of steroids, parathyroid hormone, and calcitonin in postmenopausal women during the year following hip fracture : Effect of location of fracture and age. In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 1999 ; Vol. 54, No. 9.
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AU - Michael, Roger H.

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AU - Hebel, J. Richard

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