Abstract
Background. Hip fracture in the aged is a major health problem, especially considering the increasing proportion of the elderly in the population. This study examines changes in circulating levels of hormones, which are purported to affect bone metabolism, in response to hip fracture in postmenopausal women. Methods. Patients consisted of women ages 65 and older who had surgery within 2 days of fracture. Serum samples were obtained at 3, 10, 60, 180, and 360 days postfracture. Healthy women without hip fractures from the same age range served as a control group (n=17). Hormones were determined by radioimmunoassay. Subjects with fractures in the neck region of the femur (n=78) were compared to subjects with fractures in the trochanteric region (n=88). Results. Estrone concentration (47.6 ± 5.7 pg/mL; mean ± SEM) at 3 days postfracture was elevated (p
| Original language | English (US) |
|---|---|
| Journal | Journals of Gerontology - Series A Biological Sciences and Medical Sciences |
| Volume | 54 |
| Issue number | 9 |
| State | Published - Sep 1999 |
| Externally published | Yes |
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ASJC Scopus subject areas
- Aging
Cite this
Serum concentrations of steroids, parathyroid hormone, and calcitonin in postmenopausal women during the year following hip fracture : Effect of location of fracture and age. / Dubin, Norman H.; Monahan, Lauren K.; Yu-Yahiro, Janet A.; Michael, Roger H.; Zimmerman, Sheryl I.; Hawkes, William; Hebel, J. Richard; Fox, Kathleen M.; Magaziner, Jay.
In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences, Vol. 54, No. 9, 09.1999.Research output: Contribution to journal › Article
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TY - JOUR
T1 - Serum concentrations of steroids, parathyroid hormone, and calcitonin in postmenopausal women during the year following hip fracture
T2 - Effect of location of fracture and age
AU - Dubin, Norman H.
AU - Monahan, Lauren K.
AU - Yu-Yahiro, Janet A.
AU - Michael, Roger H.
AU - Zimmerman, Sheryl I.
AU - Hawkes, William
AU - Hebel, J. Richard
AU - Fox, Kathleen M.
AU - Magaziner, Jay
PY - 1999/9
Y1 - 1999/9
N2 - Background. Hip fracture in the aged is a major health problem, especially considering the increasing proportion of the elderly in the population. This study examines changes in circulating levels of hormones, which are purported to affect bone metabolism, in response to hip fracture in postmenopausal women. Methods. Patients consisted of women ages 65 and older who had surgery within 2 days of fracture. Serum samples were obtained at 3, 10, 60, 180, and 360 days postfracture. Healthy women without hip fractures from the same age range served as a control group (n=17). Hormones were determined by radioimmunoassay. Subjects with fractures in the neck region of the femur (n=78) were compared to subjects with fractures in the trochanteric region (n=88). Results. Estrone concentration (47.6 ± 5.7 pg/mL; mean ± SEM) at 3 days postfracture was elevated (p
AB - Background. Hip fracture in the aged is a major health problem, especially considering the increasing proportion of the elderly in the population. This study examines changes in circulating levels of hormones, which are purported to affect bone metabolism, in response to hip fracture in postmenopausal women. Methods. Patients consisted of women ages 65 and older who had surgery within 2 days of fracture. Serum samples were obtained at 3, 10, 60, 180, and 360 days postfracture. Healthy women without hip fractures from the same age range served as a control group (n=17). Hormones were determined by radioimmunoassay. Subjects with fractures in the neck region of the femur (n=78) were compared to subjects with fractures in the trochanteric region (n=88). Results. Estrone concentration (47.6 ± 5.7 pg/mL; mean ± SEM) at 3 days postfracture was elevated (p
UR - http://www.scopus.com/inward/record.url?scp=0032869071&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0032869071&partnerID=8YFLogxK
M3 - Article
C2 - 10536650
AN - SCOPUS:0032869071
VL - 54
JO - Journals of Gerontology - Series A Biological Sciences and Medical Sciences
JF - Journals of Gerontology - Series A Biological Sciences and Medical Sciences
SN - 1079-5006
IS - 9
ER -