Serum concentrations of polyfluoroalkyl compounds in Faroese whale meat consumers

Pal Weihe, Kayoko Kato, Antonia M. Calafat, Flemming Nielsen, Amal Wanigatunga, Larry L. Needham, Philippe Grand Jean

Research output: Contribution to journalArticle

Abstract

To learn the extent of human exposure to polyfluoroalkyl compounds (PFCs) in a remote fishing population, we measured, in Faroese children and pregnant women, the serum concentrations of nine PFCs, including perfluorooctane sulfonate (PFOS), perfluorooctanoate (PFOA), and perfluorononanoate (PFNA), by using online solid-phase extraction coupled to isotope dilution high-performance liquid chromatography-tandem mass spectrometry. The serum samples analyzed had been collected between 1993 and 2005 from 103 children 7 years of age, 79 of these children at 14 years of age, and from 12 pregnant women and their children 5 years later. PFOS was detected in all samples analyzed, and both PFOA and PFNA were detected in all but one of the samples. The concentrations found are comparableto those reported elsewhere. Correlations between paired concentrations were poor. However, PFOS and PFNA concentrations correlated well with the frequency of pilot whale dinners and with concentrations of mercury and polychlorinated biphenyls. One whale meal every two weeks increased the PFOS concentration in 14-year-olds by about 25% and PFNA by 50%. The high frequency of detection of most PFCs suggests widespread exposure in the Faroe Islands already by the early 1990s, with whale meat being an important source.

Original languageEnglish (US)
Pages (from-to)6291-6295
Number of pages5
JournalEnvironmental Science and Technology
Volume42
Issue number16
DOIs
StatePublished - Aug 15 2008
Externally publishedYes

Fingerprint

perfluorooctanoic acid
Meats
sulfonate
whale
meat
serum
Polychlorinated Biphenyls
High performance liquid chromatography
Mercury
Isotopes
Dilution
Mass spectrometry
liquid chromatography
PCB
fishing
dilution
mass spectrometry
isotope
hexadecafluoro-nonanoic acid
perfluorooctane sulfonic acid

ASJC Scopus subject areas

  • Chemistry(all)
  • Environmental Chemistry

Cite this

Serum concentrations of polyfluoroalkyl compounds in Faroese whale meat consumers. / Weihe, Pal; Kato, Kayoko; Calafat, Antonia M.; Nielsen, Flemming; Wanigatunga, Amal; Needham, Larry L.; Jean, Philippe Grand.

In: Environmental Science and Technology, Vol. 42, No. 16, 15.08.2008, p. 6291-6295.

Research output: Contribution to journalArticle

Weihe, P, Kato, K, Calafat, AM, Nielsen, F, Wanigatunga, A, Needham, LL & Jean, PG 2008, 'Serum concentrations of polyfluoroalkyl compounds in Faroese whale meat consumers', Environmental Science and Technology, vol. 42, no. 16, pp. 6291-6295. https://doi.org/10.1021/es800695m
Weihe, Pal ; Kato, Kayoko ; Calafat, Antonia M. ; Nielsen, Flemming ; Wanigatunga, Amal ; Needham, Larry L. ; Jean, Philippe Grand. / Serum concentrations of polyfluoroalkyl compounds in Faroese whale meat consumers. In: Environmental Science and Technology. 2008 ; Vol. 42, No. 16. pp. 6291-6295.
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