Sertraline in the treatment of severe aggressiveness in Huntington's disease

Neal G. Ranen; John R. Lipsey; Glenn Treisman; Christopher A. Ross

doi:10.1176/jnp.8.3.338

Sertraline in the treatment of severe aggressiveness in Huntington's disease

Neal G. Ranen, John R. Lipsey, Glenn Treisman, Christopher A. Ross

School of Medicine

Research output: Contribution to journal › Article › peer-review

Abstract

Sertraline, a selective serotonin reuptake inhibitor, was used to treat two consecutive cases of genetically confirmed Huntington's disease in which severe irritability and aggressiveness required inpatient admission. The complete cessation of aggressive behavior in both cases has been maintained on follow-up. This report adds to the literature implicating serotonergic mechanisms in irritability and aggressiveness in both neuropsychiatric and idiopathic psychiatric disorders.

Original language	English (US)
Pages (from-to)	338-340
Number of pages	3
Journal	Journal of Neuropsychiatry and Clinical Neurosciences
Volume	8
Issue number	3
DOIs	https://doi.org/10.1176/jnp.8.3.338
State	Published - 1996

ASJC Scopus subject areas

Clinical Neurology
Psychiatry and Mental health

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