Sertraline in the treatment of severe aggressiveness in Huntington's disease

Research output: Contribution to journalArticlepeer-review


Sertraline, a selective serotonin reuptake inhibitor, was used to treat two consecutive cases of genetically confirmed Huntington's disease in which severe irritability and aggressiveness required inpatient admission. The complete cessation of aggressive behavior in both cases has been maintained on follow-up. This report adds to the literature implicating serotonergic mechanisms in irritability and aggressiveness in both neuropsychiatric and idiopathic psychiatric disorders.

Original languageEnglish (US)
Pages (from-to)338-340
Number of pages3
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Issue number3
StatePublished - 1996

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health


Dive into the research topics of 'Sertraline in the treatment of severe aggressiveness in Huntington's disease'. Together they form a unique fingerprint.

Cite this