Sertraline in the treatment of severe aggressiveness in Huntington's disease

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Abstract

Sertraline, a selective serotonin reuptake inhibitor, was used to treat two consecutive cases of genetically confirmed Huntington's disease in which severe irritability and aggressiveness required inpatient admission. The complete cessation of aggressive behavior in both cases has been maintained on follow-up. This report adds to the literature implicating serotonergic mechanisms in irritability and aggressiveness in both neuropsychiatric and idiopathic psychiatric disorders.

Original languageEnglish (US)
Pages (from-to)338-340
Number of pages3
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Volume8
Issue number3
DOIs
StatePublished - 1996

ASJC Scopus subject areas

  • Clinical Neurology
  • Psychiatry and Mental health

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