Serrated adenomas

Wilfredo E. Jesus-Monge, Carmen Gonzalez-Keelan, Marcia Cruz-Correa

Research output: Contribution to journalArticle

Abstract

Serrated adenomas are categorized as sessile serrated adenomas (SSAs) and traditional serrated adenomas (TSAs). SSAs are more prevalent in the proximal colon and lack classic dysplasia, whereas TSAs are more prevalent in the rectosigmoid and have cytologic dysplasia. Serrated adenomas may progress to colorectal adenocarcinoma through diverse molecular alterations. Colonoscopy is the only test for the early detection of serrated adenomas that allows inspection of the entire colon and same-session biopsy sampling or polypectomy, if necessary. If an endoscopic biopsy at the right colon reveals SSA without cytologic dysplasia or biopsy at the rectosigmoid reveals SSA or TSA, those polyps should be excised or surgically resected as necessary. Postpolypectomy surveillance for removed SSAs without dysplasia and TSAs must be performed at 5- and 3-year intervals, respectively, with colonoscopy to prevent recurrence and progression to colorectal adenocarcinoma.

Original languageEnglish (US)
Pages (from-to)420-427
Number of pages8
JournalCurrent Gastroenterology Reports
Volume11
Issue number5
DOIs
StatePublished - 2009
Externally publishedYes

ASJC Scopus subject areas

  • Gastroenterology

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  • Cite this

    Jesus-Monge, W. E., Gonzalez-Keelan, C., & Cruz-Correa, M. (2009). Serrated adenomas. Current Gastroenterology Reports, 11(5), 420-427. https://doi.org/10.1007/s11894-009-0063-x