Serotonin, histamine, and the arthus phenomenon

T. Phillip Waalkes, Harriette Coburn

Research output: Contribution to journalArticle


Serotonin has been shown to be released during anaphylaxis in the rabbit. The possibility that this amine might be an etiological factor in the formation of the Arthus phenomenon was considered. Because the reaction develops readily in rabbits depleted of serotonin by reserpine, it appears doubtful that this amine is of importance in the production of the lesion.

Original languageEnglish (US)
Pages (from-to)181-184
Number of pages4
JournalJournal of Allergy
Issue number2
StatePublished - Jan 1 1960

ASJC Scopus subject areas

  • Medicine(all)

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