Seroprevalence and cofactors of HTLV-I infection in Tumaco, Colombia

J. M. Trujillo, M. Concha, Alvaro Munoz, G. Bergonzoli, C. Mora, I. Borrero, C. J. Gibbs, C. Arango

Research output: Contribution to journalArticle

Abstract

This study presents an analysis of the factors associated with HTLV-I seroprevalence in the endemic area of Tumaco, Colombia. During June to August 1988, 1,077 individuals were selected at random from a population of 45,594. The overall prevalence rate of HTLV-I antibodies was 2.8%. Among females prevalence was significantly higher (p <0.02) than among males. Rates increased substantially with age. HTLV-I prevalence among individuals with history of use of intravenous medications was significantly higher (p <0.001) than in those without such history. Logistic regression analysis included age in years, indicators for male gender, and for i.v. injections, and their interactions. Age was very strongly associated to HTLV-I infection among females. At early ages prevalence was not different between sexes, but females presented a significantly higher rate than males after age 42. History of i.v. administered medications was very strongly associated in the univariate analysis and, although significance was borderline in the multivariate analysis, it had the effect of doubling the odds of HTLV-I infection.

Original languageEnglish (US)
Pages (from-to)651-657
Number of pages7
JournalAIDS Research and Human Retroviruses
Volume8
Issue number5
StatePublished - 1992

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HTLV-I Infections
Colombia
Seroepidemiologic Studies
Human T-lymphotropic virus 1
HTLV-I Antibodies
Statistical Factor Analysis
Multivariate Analysis
Logistic Models
History
Regression Analysis
Injections
Population

ASJC Scopus subject areas

  • Immunology
  • Virology

Cite this

Trujillo, J. M., Concha, M., Munoz, A., Bergonzoli, G., Mora, C., Borrero, I., ... Arango, C. (1992). Seroprevalence and cofactors of HTLV-I infection in Tumaco, Colombia. AIDS Research and Human Retroviruses, 8(5), 651-657.

Seroprevalence and cofactors of HTLV-I infection in Tumaco, Colombia. / Trujillo, J. M.; Concha, M.; Munoz, Alvaro; Bergonzoli, G.; Mora, C.; Borrero, I.; Gibbs, C. J.; Arango, C.

In: AIDS Research and Human Retroviruses, Vol. 8, No. 5, 1992, p. 651-657.

Research output: Contribution to journalArticle

Trujillo, JM, Concha, M, Munoz, A, Bergonzoli, G, Mora, C, Borrero, I, Gibbs, CJ & Arango, C 1992, 'Seroprevalence and cofactors of HTLV-I infection in Tumaco, Colombia', AIDS Research and Human Retroviruses, vol. 8, no. 5, pp. 651-657.
Trujillo JM, Concha M, Munoz A, Bergonzoli G, Mora C, Borrero I et al. Seroprevalence and cofactors of HTLV-I infection in Tumaco, Colombia. AIDS Research and Human Retroviruses. 1992;8(5):651-657.
Trujillo, J. M. ; Concha, M. ; Munoz, Alvaro ; Bergonzoli, G. ; Mora, C. ; Borrero, I. ; Gibbs, C. J. ; Arango, C. / Seroprevalence and cofactors of HTLV-I infection in Tumaco, Colombia. In: AIDS Research and Human Retroviruses. 1992 ; Vol. 8, No. 5. pp. 651-657.
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