Serological investigation of the possibility of congenital transmission of papovavirus JC

R. Daniel, K. Shah, D. Madden, S. Stagno

Research output: Contribution to journalArticlepeer-review

Abstract

In an examination of paired sera from pregnant women, 9 of 57 women who had JC virus antibodies in their first specimens exhibited virus reactivation, as judged by a 4-fold or greater rise in JC virus hemagglutination-inhibiting antibodies; 43 women remained seronegative through pregnancy. JC virus-specific immunoglobulin M was not demonstrated in umbilical cord sera of 6 infants born to mothers showing reactivation or in 300 additional umbilical cord sera from normal pregnancies.

Original languageEnglish (US)
Pages (from-to)319-321
Number of pages3
JournalInfection and immunity
Volume33
Issue number1
DOIs
StatePublished - 1981

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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