Serological evidence of human granulocytic ehrlichiosis in Switzerland

N. Pusterla; R. Weber; C. Wolfensberger; G. Schär; R. Zbinden; W. Fierz; J. E. Madigan; J. S. Dumler; H. Lutz

doi:10.1007/BF01691120

Serological evidence of human granulocytic ehrlichiosis in Switzerland

N. Pusterla, R. Weber, C. Wolfensberger, G. Schär, R. Zbinden, W. Fierz, J. E. Madigan, J. S. Dumler, H. Lutz

Research output: Contribution to journal › Article › peer-review

52 Scopus citations

Abstract

To investigate whether human granulocytic ehrlichiosis (HGE) is prevalent in Switzerland, 1515 human serum samples from individuals with different risks for tick exposure were tested for antibodies to Ehrlichia phagocytophila, a surrogate marker of the agent of HGE. The distribution of titres showed marked differences between sera of individuals with no or low risk for tick exposure and those with a high risk. The results of serological testing provided evidence of HGE in Switzerland as well as evidence of two types of coinfections, those with the agent of HGE and Borrelia burgdorferi, and those with the agent of HGE and the central European tickborne encephalitis virus.

Original language	English (US)
Pages (from-to)	207-209
Number of pages	3
Journal	European Journal of Clinical Microbiology and Infectious Diseases
Volume	17
Issue number	3
DOIs	https://doi.org/10.1007/BF01691120
State	Published - 1998
Externally published	Yes

Keywords

Human granulocytic ehrlichiosis
Indirect immunofluorescent antibody test
Prevalence
Switzerland

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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10.1007/BF01691120

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@article{113449e3ee464838b496b33acec4f77a,

title = "Serological evidence of human granulocytic ehrlichiosis in Switzerland",

abstract = "To investigate whether human granulocytic ehrlichiosis (HGE) is prevalent in Switzerland, 1515 human serum samples from individuals with different risks for tick exposure were tested for antibodies to Ehrlichia phagocytophila, a surrogate marker of the agent of HGE. The distribution of titres showed marked differences between sera of individuals with no or low risk for tick exposure and those with a high risk. The results of serological testing provided evidence of HGE in Switzerland as well as evidence of two types of coinfections, those with the agent of HGE and Borrelia burgdorferi, and those with the agent of HGE and the central European tickborne encephalitis virus.",

keywords = "Human granulocytic ehrlichiosis, Indirect immunofluorescent antibody test, Prevalence, Switzerland",

author = "N. Pusterla and R. Weber and C. Wolfensberger and G. Sch{\"a}r and R. Zbinden and W. Fierz and Madigan, {J. E.} and Dumler, {J. S.} and H. Lutz",

note = "Funding Information: Acknowledgements This study was supported by the Kommis-sion zur F~Srderung des akademischen Nachwuchses and the Swiss Federal Office of Public Health. The authors wish to thank Dr. med. Walter Bossard, Dr. reed. David Nadal, and Dr. med. vet. Felix Grimm for supplying serum samples.",

year = "1998",

doi = "10.1007/BF01691120",

language = "English (US)",

volume = "17",

pages = "207--209",

journal = "European Journal of Clinical Microbiology and Infectious Diseases",

issn = "0934-9723",

publisher = "Springer Verlag",

number = "3",

}

TY - JOUR

T1 - Serological evidence of human granulocytic ehrlichiosis in Switzerland

AU - Pusterla, N.

AU - Weber, R.

AU - Wolfensberger, C.

AU - Schär, G.

AU - Zbinden, R.

AU - Fierz, W.

AU - Madigan, J. E.

AU - Dumler, J. S.

AU - Lutz, H.

N1 - Funding Information: Acknowledgements This study was supported by the Kommis-sion zur F~Srderung des akademischen Nachwuchses and the Swiss Federal Office of Public Health. The authors wish to thank Dr. med. Walter Bossard, Dr. reed. David Nadal, and Dr. med. vet. Felix Grimm for supplying serum samples.

PY - 1998

Y1 - 1998

N2 - To investigate whether human granulocytic ehrlichiosis (HGE) is prevalent in Switzerland, 1515 human serum samples from individuals with different risks for tick exposure were tested for antibodies to Ehrlichia phagocytophila, a surrogate marker of the agent of HGE. The distribution of titres showed marked differences between sera of individuals with no or low risk for tick exposure and those with a high risk. The results of serological testing provided evidence of HGE in Switzerland as well as evidence of two types of coinfections, those with the agent of HGE and Borrelia burgdorferi, and those with the agent of HGE and the central European tickborne encephalitis virus.

AB - To investigate whether human granulocytic ehrlichiosis (HGE) is prevalent in Switzerland, 1515 human serum samples from individuals with different risks for tick exposure were tested for antibodies to Ehrlichia phagocytophila, a surrogate marker of the agent of HGE. The distribution of titres showed marked differences between sera of individuals with no or low risk for tick exposure and those with a high risk. The results of serological testing provided evidence of HGE in Switzerland as well as evidence of two types of coinfections, those with the agent of HGE and Borrelia burgdorferi, and those with the agent of HGE and the central European tickborne encephalitis virus.

KW - Human granulocytic ehrlichiosis

KW - Indirect immunofluorescent antibody test

KW - Prevalence

KW - Switzerland

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JO - European Journal of Clinical Microbiology and Infectious Diseases

JF - European Journal of Clinical Microbiology and Infectious Diseases

IS - 3

ER -

Serological evidence of human granulocytic ehrlichiosis in Switzerland

Abstract

Keywords

ASJC Scopus subject areas

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