Seroepidemiology of hepatitis b virus in the Philippines

Augusto L. Lingao, Ernesto O. Domingo, Sheila West, Cesar M. Reyes, Sergio Gasmen, George Viterbo, Edith Tiu, Mary Ann Lansang

Research output: Contribution to journalArticle

Abstract

Hepatitis B virus markers were studied in 2,842 Philippine rural subjects from four villages in 1979-1982. The prevalence of hepatitis B surface antigen (HBsAg) and all markers for hepatitis B virus averaged 12% and 58%, respectively, in these rural populations. It is estimated that five million Filipinos are HBsAg positive. The rural age-specific HBsAg prevalence shows an "early peak" (In persons 3-4-years-old) In two communities and a "late peak" (In persons 30-40-years-old) In the other two communities. Family studies suggest that the prevalence of HBsAg and hepatitis B e antigen (HBeAg) among parents of the young children in an "early peak" and a "late peak" village cannot fully account for the difference in the patterns of prevalence of all markers, or the HBsAg marker. Horizontal intrafamilial and extrafamilial transmission may also be significant. Further research is needed on risk factors for hepatitis B virus infection.

Original languageEnglish (US)
Pages (from-to)473-480
Number of pages8
JournalAmerican journal of epidemiology
Volume123
Issue number3
DOIs
StatePublished - Mar 1986

Keywords

  • Family
  • Hepatitis B
  • Hepatitis B surface antigens
  • Serology

ASJC Scopus subject areas

  • Epidemiology

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  • Cite this

    Lingao, A. L., Domingo, E. O., West, S., Reyes, C. M., Gasmen, S., Viterbo, G., Tiu, E., & Lansang, M. A. (1986). Seroepidemiology of hepatitis b virus in the Philippines. American journal of epidemiology, 123(3), 473-480. https://doi.org/10.1093/oxfordjournals.aje.a114262