Serine proteinases in human cutaneous mastocytosis

J. E. Fräki, N. M. Schechter, G. S. Lazarus

Research output: Contribution to journalArticlepeer-review

Abstract

The main chymotryptic and tryptic proteinases of human skin were found in high-salt extracts of human dermis. The levels of these enzymes were markedly increased in salt extracts of human cutaneous mastocytosis as compared to the levels found in extracts of involved skin from the same patients, human cutaneous hemangiomas, and normal human skin. These data suggest that the chymotryptic and tryptic proteinases of human skin are primarily of mast-cell origin.

Original languageEnglish (US)
Pages (from-to)363-366
Number of pages4
JournalArchives of Dermatological Research
Volume278
Issue number5
DOIs
StatePublished - Jul 1 1986
Externally publishedYes

Keywords

  • Cutaneous mastocytosis
  • Serine proteinases

ASJC Scopus subject areas

  • Dermatology

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