Serine proteinases in human cutaneous mastocytosis

J. E. Fräki; N. M. Schechter; G. S. Lazarus

doi:10.1007/BF00418163

Serine proteinases in human cutaneous mastocytosis

J. E. Fräki, N. M. Schechter, G. S. Lazarus

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

The main chymotryptic and tryptic proteinases of human skin were found in high-salt extracts of human dermis. The levels of these enzymes were markedly increased in salt extracts of human cutaneous mastocytosis as compared to the levels found in extracts of involved skin from the same patients, human cutaneous hemangiomas, and normal human skin. These data suggest that the chymotryptic and tryptic proteinases of human skin are primarily of mast-cell origin.

Original language	English (US)
Pages (from-to)	363-366
Number of pages	4
Journal	Archives of Dermatological Research
Volume	278
Issue number	5
DOIs	https://doi.org/10.1007/BF00418163
State	Published - Jul 1 1986
Externally published	Yes

Keywords

Cutaneous mastocytosis
Serine proteinases

ASJC Scopus subject areas

Dermatology

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10.1007/BF00418163

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title = "Serine proteinases in human cutaneous mastocytosis",

abstract = "The main chymotryptic and tryptic proteinases of human skin were found in high-salt extracts of human dermis. The levels of these enzymes were markedly increased in salt extracts of human cutaneous mastocytosis as compared to the levels found in extracts of involved skin from the same patients, human cutaneous hemangiomas, and normal human skin. These data suggest that the chymotryptic and tryptic proteinases of human skin are primarily of mast-cell origin.",

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year = "1986",

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AU - Fräki, J. E.

AU - Schechter, N. M.

AU - Lazarus, G. S.

PY - 1986/7/1

Y1 - 1986/7/1

N2 - The main chymotryptic and tryptic proteinases of human skin were found in high-salt extracts of human dermis. The levels of these enzymes were markedly increased in salt extracts of human cutaneous mastocytosis as compared to the levels found in extracts of involved skin from the same patients, human cutaneous hemangiomas, and normal human skin. These data suggest that the chymotryptic and tryptic proteinases of human skin are primarily of mast-cell origin.

AB - The main chymotryptic and tryptic proteinases of human skin were found in high-salt extracts of human dermis. The levels of these enzymes were markedly increased in salt extracts of human cutaneous mastocytosis as compared to the levels found in extracts of involved skin from the same patients, human cutaneous hemangiomas, and normal human skin. These data suggest that the chymotryptic and tryptic proteinases of human skin are primarily of mast-cell origin.

KW - Cutaneous mastocytosis

KW - Serine proteinases

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ER -

Serine proteinases in human cutaneous mastocytosis

Abstract

Keywords

ASJC Scopus subject areas

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