Sequential roles of primary somatosensory cortex and posterior parietal cortex in tactile-visual cross-modal working memory: A single-pulse transcranial magnetic stimulation (spTMS) study

Yixuan Ku, Di Zhao, Ning Hao, Yi Hu, Mark Bodner, Yong Di Zhou

Research output: Contribution to journalArticle

Abstract

Background Both monkey neurophysiological and human EEG studies have shown that association cortices, as well as primary sensory cortical areas, play an essential role in sequential neural processes underlying cross-modal working memory.

Objective The present study aims to further examine causal and sequential roles of the primary sensory cortex and association cortex in cross-modal working memory.

Methods Individual MRI-based single-pulse transcranial magnetic stimulation (spTMS) was applied to bilateral primary somatosensory cortices (SI) and the contralateral posterior parietal cortex (PPC), while participants were performing a tactile-visual cross-modal delayed matching-to-sample task. Time points of spTMS were 300 ms, 600 ms, 900 ms after the onset of the tactile sample stimulus in the task.

Results The accuracy of task performance and reaction time were significantly impaired when spTMS was applied to the contralateral SI at 300 ms. Significant impairment on performance accuracy was also observed when the contralateral PPC was stimulated at 600 ms.

Conclusion SI and PPC play sequential and distinct roles in neural processes of cross-modal associations and working memory.

Original languageEnglish (US)
Pages (from-to)88-91
Number of pages4
JournalBrain Stimulation
Volume8
Issue number1
DOIs
StatePublished - Jan 1 2015

Fingerprint

Parietal Lobe
Somatosensory Cortex
Transcranial Magnetic Stimulation
Touch
Short-Term Memory
Task Performance and Analysis
Reaction Time
Haplorhini
Electroencephalography

Keywords

  • Cross-modal
  • Primary somatosensory cortex
  • spTMS
  • Working memory

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)
  • Biophysics
  • Medicine(all)

Cite this

Sequential roles of primary somatosensory cortex and posterior parietal cortex in tactile-visual cross-modal working memory : A single-pulse transcranial magnetic stimulation (spTMS) study. / Ku, Yixuan; Zhao, Di; Hao, Ning; Hu, Yi; Bodner, Mark; Zhou, Yong Di.

In: Brain Stimulation, Vol. 8, No. 1, 01.01.2015, p. 88-91.

Research output: Contribution to journalArticle

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