Sequence of the flaA (cheC) locus of Escherichia coli and discovery of a new gene

S. C. Kup, D. E. Koshland

Research output: Contribution to journalArticlepeer-review

Abstract

The flaA (cheC) locus from Escherichia coli is important in controlling the rotational direction of flagella during chemotaxis. The locus was sequenced, and a site of transcriptional initiation was determined. Two reading frames, flaAI and flaAII, span the locus. flaAII corresponds to certain flaA and cheC mutations, and has some unusual features in the predicted secondary structure. flaAI, however, has not been identified previously, but a flaAI deletion, which produced a truncated FlaAI peptide in minicells, clearly identified the FlaAI protein.

Original languageEnglish (US)
Pages (from-to)1007-1012
Number of pages6
JournalJournal of bacteriology
Volume166
Issue number3
DOIs
StatePublished - 1986
Externally publishedYes

ASJC Scopus subject areas

  • Microbiology
  • Molecular Biology

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