Septic and technical complications of central venous catheterization. A prospective study of 200 consecutive patients

J. V. Sitzmann, T. R. Townsend, M. C. Siler, John Bartlett

Research output: Contribution to journalArticle

Abstract

The results of central venous catheterization for total parenteral nutrition were prospectively evaluated in 200 consecutive patients. All catheters were fabricated of polyurethane tubing inserted by the Seldinger technique. Two hundred sixty-three lines were inserted in 200 patients for a total of 4103 days. Major complications occurred in 2.3% patients. Twenty-four per cent of catheters were associated with suspected sepsis; of these, 52% were removed directly and 48% were changed over a guidewire. The total catheter sepsis rate was 5.7%. The incidence of sepsis correlated with the number of attempts to insert the line and with positive skin cultures. These data indicate that: (1) use of the Seldinger technique to insert nonthrombogenic flexible catheters results in lower technical morbidity; (2) the incidence of established infection is much lower than the incidence of suspected sepsis; (3) guidewire change may be performed without risk to the patient or interruption of therapy; (4) sepsis rates can be decreased by reducing the number of attempts to catheterize the subclavian vein; and (5) sepsis rates correlate with positive skin cultures at the insertion site.

Original languageEnglish (US)
Pages (from-to)766-770
Number of pages5
JournalAnnals of Surgery
Volume202
Issue number6
StatePublished - 1985

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Central Venous Catheterization
Sepsis
Prospective Studies
Catheters
Incidence
Subclavian Vein
Skin
Polyurethanes
Total Parenteral Nutrition
Morbidity
Infection

ASJC Scopus subject areas

  • Surgery

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Septic and technical complications of central venous catheterization. A prospective study of 200 consecutive patients. / Sitzmann, J. V.; Townsend, T. R.; Siler, M. C.; Bartlett, John.

In: Annals of Surgery, Vol. 202, No. 6, 1985, p. 766-770.

Research output: Contribution to journalArticle

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