Sensitivity of monocyte subpopulations to cyclosporine arachidonate metabolism and in vitro antigen presentation

A. H. Esa; D. G. Paxman; S. J. Noga; A. D. Hess

Sensitivity of monocyte subpopulations to cyclosporine arachidonate metabolism and in vitro antigen presentation

A. H. Esa, D. G. Paxman, S. J. Noga, A. D. Hess

School of Medicine

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

In this study, we examined the effects of CsA on the antigen presentation capacity of two monocyte subpopulations and the role of CsA-caused PGE₂ release in the CsA-induced inhibition of monocyte antigen presentation. Our results suggest that a monocyte subpopulation that efficiently presents antigens is relatively more sensitive to CsA than a subpopulation that preferentially induces immunosuppression.

Original language	English (US)
Pages (from-to)	80-86
Number of pages	7
Journal	Transplantation proceedings
Volume	20
Issue number	2 SUPPL. 2
State	Published - 1988

ASJC Scopus subject areas

Surgery
Transplantation

Cite this

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title = "Sensitivity of monocyte subpopulations to cyclosporine arachidonate metabolism and in vitro antigen presentation",

abstract = "In this study, we examined the effects of CsA on the antigen presentation capacity of two monocyte subpopulations and the role of CsA-caused PGE2 release in the CsA-induced inhibition of monocyte antigen presentation. Our results suggest that a monocyte subpopulation that efficiently presents antigens is relatively more sensitive to CsA than a subpopulation that preferentially induces immunosuppression.",

author = "Esa, {A. H.} and Paxman, {D. G.} and Noga, {S. J.} and Hess, {A. D.}",

year = "1988",

language = "English (US)",

volume = "20",

pages = "80--86",

journal = "Transplantation proceedings",

issn = "0041-1345",

publisher = "Elsevier USA",

number = "2 SUPPL. 2",

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TY - JOUR

T1 - Sensitivity of monocyte subpopulations to cyclosporine arachidonate metabolism and in vitro antigen presentation

AU - Esa, A. H.

AU - Paxman, D. G.

AU - Noga, S. J.

AU - Hess, A. D.

PY - 1988

Y1 - 1988

N2 - In this study, we examined the effects of CsA on the antigen presentation capacity of two monocyte subpopulations and the role of CsA-caused PGE2 release in the CsA-induced inhibition of monocyte antigen presentation. Our results suggest that a monocyte subpopulation that efficiently presents antigens is relatively more sensitive to CsA than a subpopulation that preferentially induces immunosuppression.

AB - In this study, we examined the effects of CsA on the antigen presentation capacity of two monocyte subpopulations and the role of CsA-caused PGE2 release in the CsA-induced inhibition of monocyte antigen presentation. Our results suggest that a monocyte subpopulation that efficiently presents antigens is relatively more sensitive to CsA than a subpopulation that preferentially induces immunosuppression.

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M3 - Article

C2 - 3129847

AN - SCOPUS:0023925015

SN - 0041-1345

VL - 20

SP - 80

EP - 86

JO - Transplantation proceedings

JF - Transplantation proceedings

IS - 2 SUPPL. 2

ER -

Sensitivity of monocyte subpopulations to cyclosporine arachidonate metabolism and in vitro antigen presentation

Abstract

ASJC Scopus subject areas

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