Sensitivity of monocyte subpopulations to cyclosporine arachidonate metabolism and in vitro antigen presentation

A. H. Esa, D. G. Paxman, S. J. Noga, A. D. Hess

Research output: Contribution to journalArticlepeer-review

Abstract

In this study, we examined the effects of CsA on the antigen presentation capacity of two monocyte subpopulations and the role of CsA-caused PGE2 release in the CsA-induced inhibition of monocyte antigen presentation. Our results suggest that a monocyte subpopulation that efficiently presents antigens is relatively more sensitive to CsA than a subpopulation that preferentially induces immunosuppression.

Original languageEnglish (US)
Pages (from-to)80-86
Number of pages7
JournalTransplantation proceedings
Volume20
Issue number2 SUPPL. 2
StatePublished - 1988

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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