Sensitivity of in vivo x-ray fluorescence determination of skeletal lead stores

Rosemary K. Sokas; Anatole Besarab; Melissa A. McDiarmid; Irving M. Shapiro; Peter Bloch

doi:10.1080/00039896.1990.10118744

Sensitivity of in vivo x-ray fluorescence determination of skeletal lead stores

Rosemary K. Sokas, Anatole Besarab, Melissa A. McDiarmid, Irving M. Shapiro, Peter Bloch

Bloomberg School of Public Health

Research output: Contribution to journal › Article › peer-review

11 Scopus citations

Abstract

Eighteen patients with known past occupational lead exposure underwent parenteral diagnostic chelation with ethylenediaminetetraacetic acid and x-ray fluorescent determination of in vivo skeletal lead stores at the distal styloid process of the ulna and at the temporal base bone using a cobalt 57 source and measuring lead K_a x-rays. X-ray fluorescent lead measurements in both locations correlated with results of diagnostic chelation. Using a post-chelation urinary excretion of > 600μ lead/24 h as the definition of “high-” lead stores, sensitivity of x-ray fluorescence at the wrist and temple was 56% and 39%, respectively.

Original language	English (US)
Pages (from-to)	268-272
Number of pages	5
Journal	Archives of Environmental Health
Volume	45
Issue number	5
DOIs	https://doi.org/10.1080/00039896.1990.10118744
State	Published - 1990

ASJC Scopus subject areas

Health, Toxicology and Mutagenesis
General Environmental Science
Environmental Chemistry
Public Health, Environmental and Occupational Health

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10.1080/00039896.1990.10118744

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abstract = "Eighteen patients with known past occupational lead exposure underwent parenteral diagnostic chelation with ethylenediaminetetraacetic acid and x-ray fluorescent determination of in vivo skeletal lead stores at the distal styloid process of the ulna and at the temporal base bone using a cobalt 57 source and measuring lead Ka x-rays. X-ray fluorescent lead measurements in both locations correlated with results of diagnostic chelation. Using a post-chelation urinary excretion of > 600μ lead/24 h as the definition of “high-” lead stores, sensitivity of x-ray fluorescence at the wrist and temple was 56% and 39%, respectively.",

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AU - Besarab, Anatole

AU - McDiarmid, Melissa A.

AU - Shapiro, Irving M.

AU - Bloch, Peter

PY - 1990

Y1 - 1990

N2 - Eighteen patients with known past occupational lead exposure underwent parenteral diagnostic chelation with ethylenediaminetetraacetic acid and x-ray fluorescent determination of in vivo skeletal lead stores at the distal styloid process of the ulna and at the temporal base bone using a cobalt 57 source and measuring lead Ka x-rays. X-ray fluorescent lead measurements in both locations correlated with results of diagnostic chelation. Using a post-chelation urinary excretion of > 600μ lead/24 h as the definition of “high-” lead stores, sensitivity of x-ray fluorescence at the wrist and temple was 56% and 39%, respectively.

AB - Eighteen patients with known past occupational lead exposure underwent parenteral diagnostic chelation with ethylenediaminetetraacetic acid and x-ray fluorescent determination of in vivo skeletal lead stores at the distal styloid process of the ulna and at the temporal base bone using a cobalt 57 source and measuring lead Ka x-rays. X-ray fluorescent lead measurements in both locations correlated with results of diagnostic chelation. Using a post-chelation urinary excretion of > 600μ lead/24 h as the definition of “high-” lead stores, sensitivity of x-ray fluorescence at the wrist and temple was 56% and 39%, respectively.

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JF - Archives of Environmental Health

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ER -

Sensitivity of in vivo x-ray fluorescence determination of skeletal lead stores

Abstract

ASJC Scopus subject areas

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