Sensitivity of in vivo x-ray fluorescence determination of skeletal lead stores

Rosemary K. Sokas, Anatole Besarab, Melissa A. McDiarmid, Irving M. Shapiro, Peter Bloch

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Eighteen patients with known past occupational lead exposure underwent parenteral diagnostic chelation with ethylenediaminetetraacetic acid and x-ray fluorescent determination of in vivo skeletal lead stores at the distal styloid process of the ulna and at the temporal base bone using a cobalt 57 source and measuring lead Ka x-rays. X-ray fluorescent lead measurements in both locations correlated with results of diagnostic chelation. Using a post-chelation urinary excretion of > 600μ lead/24 h as the definition of “high-” lead stores, sensitivity of x-ray fluorescence at the wrist and temple was 56% and 39%, respectively.

Original languageEnglish (US)
Pages (from-to)268-272
Number of pages5
JournalArchives of Environmental Health
Issue number5
StatePublished - 1990

ASJC Scopus subject areas

  • Health, Toxicology and Mutagenesis
  • Environmental Science(all)
  • Environmental Chemistry
  • Public Health, Environmental and Occupational Health


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