Semaphorins: Mediators of repulsive growth cone guidance

Research output: Contribution to journalArticle

Abstract

During development neuronal growth cones encounter a variety of guidance cues while mediating axon pathfinding, target recognition and synapse formation. It is clear that repulsive guidance mechanisms play an essential role in these processes. The semaphorin gene family, which is conserved from invertebrates to mammals, includes members that mediate repulsive guidance. Molecular and cellular analysis of this gene family is providing insight into how inhibitory cues function during neurodevelopment.

Original languageEnglish (US)
Pages (from-to)15-22
Number of pages8
JournalTrends in Cell Biology
Volume6
Issue number1
DOIs
StatePublished - Jan 1996

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Semaphorins
Growth Cones
Cues
Invertebrates
Synapses
Genes
Mammals
Axon Guidance
Recognition (Psychology)

ASJC Scopus subject areas

  • Cell Biology

Cite this

Semaphorins : Mediators of repulsive growth cone guidance. / Kolodkin, Alex L.

In: Trends in Cell Biology, Vol. 6, No. 1, 01.1996, p. 15-22.

Research output: Contribution to journalArticle

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