Semantic processing and response inhibition

Hsueh Sheng Chiang, Michael A. Motes, Raksha A. Mudar, Neena K. Rao, Sethesh Mansinghani, Matthew R. Brier, Mandy J. Maguire, Michael A Kraut, John Hart

Research output: Contribution to journalArticle

Abstract

The present study examined functional MRI (fMRI) BOLD signal changes in response to object categorization during response selection and inhibition. Young adults (N=16) completed a Go/NoGo task with varying object categorization requirements while fMRI data were recorded. Response inhibition elicited increased signal change in various brain regions, including medial frontal areas, compared with response selection. BOLD signal in an area within the right angular gyrus was increased when higher-order categorization was mandated. In addition, signal change during response inhibition varied with categorization requirements in the left inferior temporal gyrus (lIT). lIT-mediated response inhibition when inhibiting the response only required lower-order categorization, but lIT mediated both response selection and inhibition when selecting and inhibiting the response required higher-order categorization. The findings characterized mechanisms mediating response inhibition associated with semantic object categorization in the 'what' visual object memory system.

Original languageEnglish (US)
Pages (from-to)889-893
Number of pages5
JournalNeuroReport
Volume24
Issue number16
DOIs
StatePublished - Nov 13 2013

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Semantics
Temporal Lobe
Magnetic Resonance Imaging
Parietal Lobe
Inhibition (Psychology)
Young Adult
Brain

Keywords

  • categorization
  • Go/NoGo
  • object memory
  • response inhibition
  • semantic

ASJC Scopus subject areas

  • Neuroscience(all)

Cite this

Chiang, H. S., Motes, M. A., Mudar, R. A., Rao, N. K., Mansinghani, S., Brier, M. R., ... Hart, J. (2013). Semantic processing and response inhibition. NeuroReport, 24(16), 889-893. https://doi.org/10.1097/WNR.0000000000000014

Semantic processing and response inhibition. / Chiang, Hsueh Sheng; Motes, Michael A.; Mudar, Raksha A.; Rao, Neena K.; Mansinghani, Sethesh; Brier, Matthew R.; Maguire, Mandy J.; Kraut, Michael A; Hart, John.

In: NeuroReport, Vol. 24, No. 16, 13.11.2013, p. 889-893.

Research output: Contribution to journalArticle

Chiang, HS, Motes, MA, Mudar, RA, Rao, NK, Mansinghani, S, Brier, MR, Maguire, MJ, Kraut, MA & Hart, J 2013, 'Semantic processing and response inhibition', NeuroReport, vol. 24, no. 16, pp. 889-893. https://doi.org/10.1097/WNR.0000000000000014
Chiang HS, Motes MA, Mudar RA, Rao NK, Mansinghani S, Brier MR et al. Semantic processing and response inhibition. NeuroReport. 2013 Nov 13;24(16):889-893. https://doi.org/10.1097/WNR.0000000000000014
Chiang, Hsueh Sheng ; Motes, Michael A. ; Mudar, Raksha A. ; Rao, Neena K. ; Mansinghani, Sethesh ; Brier, Matthew R. ; Maguire, Mandy J. ; Kraut, Michael A ; Hart, John. / Semantic processing and response inhibition. In: NeuroReport. 2013 ; Vol. 24, No. 16. pp. 889-893.
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