Semantic priming modulates the N400, N300, and N400RP

Michael S. Franklin, Joseph Dien, James H. Neely, Elizabeth Huber, Lauren D. Waterson

Research output: Contribution to journalArticle

Abstract

Objective: To determine whether ERP components can differentiate between the semantic priming mechanisms of automatic spreading activation, expectancy, and semantic matching. Methods: The present study manipulated two factors known to differentiate semantic priming mechanisms: associations between words (forward, backward, and symmetrical) and prime-target stimulus onset asynchrony (SOA). Twenty-six participants were tested in each SOA condition while high-density 128-channel data were collected. Principal components analysis was applied to separate the ERP components. Results: Priming was observed for all conditions. Three semantic components were present: (1) the standard N400 effect for symmetric and forward priming pairs at both short and long SOAs, (2) an N300 for the long SOA symmetric priming pairs, and (3) a right-lateralized posterior N400RP for long SOA backward priming pairs. Conclusions: Results suggest that the N300 reflects expectancy, but only for categorical and/or semantic similarity priming. Results further suggest that the N400RP is a replicable ERP component that responds to semantic matching. There is also some evidence that the N400 indirectly responds to both ASA and expectancy, perhaps as part of a post-lexical updating process and that backward priming at short SOAs is different from that at long SOAs. Significance: Improved understanding of the semantic properties of the N400 and related ERP components may increase their utility for understanding language processes and for diagnostic purposes.

Original languageEnglish (US)
Pages (from-to)1053-1068
Number of pages16
JournalClinical Neurophysiology
Volume118
Issue number5
DOIs
StatePublished - May 2007
Externally publishedYes

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Semantics
Principal Component Analysis
Language

Keywords

  • Attention
  • Event related potential (ERP)
  • N400
  • Semantic priming

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Neurology
  • Sensory Systems
  • Physiology (medical)

Cite this

Franklin, M. S., Dien, J., Neely, J. H., Huber, E., & Waterson, L. D. (2007). Semantic priming modulates the N400, N300, and N400RP. Clinical Neurophysiology, 118(5), 1053-1068. https://doi.org/10.1016/j.clinph.2007.01.012

Semantic priming modulates the N400, N300, and N400RP. / Franklin, Michael S.; Dien, Joseph; Neely, James H.; Huber, Elizabeth; Waterson, Lauren D.

In: Clinical Neurophysiology, Vol. 118, No. 5, 05.2007, p. 1053-1068.

Research output: Contribution to journalArticle

Franklin, MS, Dien, J, Neely, JH, Huber, E & Waterson, LD 2007, 'Semantic priming modulates the N400, N300, and N400RP', Clinical Neurophysiology, vol. 118, no. 5, pp. 1053-1068. https://doi.org/10.1016/j.clinph.2007.01.012
Franklin MS, Dien J, Neely JH, Huber E, Waterson LD. Semantic priming modulates the N400, N300, and N400RP. Clinical Neurophysiology. 2007 May;118(5):1053-1068. https://doi.org/10.1016/j.clinph.2007.01.012
Franklin, Michael S. ; Dien, Joseph ; Neely, James H. ; Huber, Elizabeth ; Waterson, Lauren D. / Semantic priming modulates the N400, N300, and N400RP. In: Clinical Neurophysiology. 2007 ; Vol. 118, No. 5. pp. 1053-1068.
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