TY - JOUR
T1 - Self-Reported Masticatory Dysfunction and Mortality in Community Dwelling Elderly Adults
T2 - A 9-Year Follow-Up
AU - Laudisio, Alice
AU - Gemma, Antonella
AU - Fontana, Davide O.
AU - Rivera, Chiara
AU - Bandinelli, Stefania
AU - Ferrucci, Luigi
AU - Incalzi, Raffaele Antonelli
PY - 2016/12/1
Y1 - 2016/12/1
N2 - Objectives: To evaluate the association, if any, between masticatory dysfunction (MD) and mortality in older adults. Design: The Invecchiare in Chianti (InCHIANTI) Study, a cohort study with 9-year follow-up. Setting: Tuscany, Italy. Participants: Individuals aged 65 and older (N = 1,155). Measurements: MD was self-reported; Cox regression was used to assess the association between self-reported MD and 9-year all-cause mortality. This association was also evaluated after stratifying according to use of dentures. Analyses were adjusted for potential confounders, including demographic characteristics, lifestyle habits, comorbidities, nutrient intake, medications, and objective parameters. Results: Four hundred five (35%) participants reported MD. Over the 9-year follow-up, 475 (41%) subjects died. According to Cox regression analysis, self-reported MD was associated with higher mortality (relative risk (RR) = 1.23, 95% confidence interval (CI) = 1.02–1.48), after adjusting for potential confounders. In participants with self-reported MD, uncorrected edentulism was the condition associated with the greatest risk of mortality (RR = 2.10, 95% CI = 1.07–4.14); use of dentures seemed to blunt this association (RR = 1.12, 95% CI = 0.87–1.44). Conclusion: Self-reported MD, chiefly when due to uncorrected edentulism, is associated with 9-year all-cause mortality in community-dwelling elderly adults. Further studies are needed to evaluate whether the timely correction of MD using adequate dentures can increase the survival of older adults.
AB - Objectives: To evaluate the association, if any, between masticatory dysfunction (MD) and mortality in older adults. Design: The Invecchiare in Chianti (InCHIANTI) Study, a cohort study with 9-year follow-up. Setting: Tuscany, Italy. Participants: Individuals aged 65 and older (N = 1,155). Measurements: MD was self-reported; Cox regression was used to assess the association between self-reported MD and 9-year all-cause mortality. This association was also evaluated after stratifying according to use of dentures. Analyses were adjusted for potential confounders, including demographic characteristics, lifestyle habits, comorbidities, nutrient intake, medications, and objective parameters. Results: Four hundred five (35%) participants reported MD. Over the 9-year follow-up, 475 (41%) subjects died. According to Cox regression analysis, self-reported MD was associated with higher mortality (relative risk (RR) = 1.23, 95% confidence interval (CI) = 1.02–1.48), after adjusting for potential confounders. In participants with self-reported MD, uncorrected edentulism was the condition associated with the greatest risk of mortality (RR = 2.10, 95% CI = 1.07–4.14); use of dentures seemed to blunt this association (RR = 1.12, 95% CI = 0.87–1.44). Conclusion: Self-reported MD, chiefly when due to uncorrected edentulism, is associated with 9-year all-cause mortality in community-dwelling elderly adults. Further studies are needed to evaluate whether the timely correction of MD using adequate dentures can increase the survival of older adults.
KW - community-dwelling elderly adults
KW - epidemiology
KW - masticatory dysfunction
KW - mortality
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U2 - 10.1111/jgs.14331
DO - 10.1111/jgs.14331
M3 - Article
C2 - 27889908
AN - SCOPUS:85005808158
SN - 0002-8614
VL - 64
SP - 2503
EP - 2510
JO - Journal of the American Geriatrics Society
JF - Journal of the American Geriatrics Society
IS - 12
ER -