Self-Efficacy as a longitudinal predictor of perceived cognitive impairment in individuals with multiple sclerosis

Abbey Hughes, Meghan Beier, Narineh Hartoonian, Aaron P. Turner, Dagmar Amtmann, Dawn M. Ehde

Research output: Contribution to journalArticle


Abstract Objectives To determine whether self-efficacy longitudinally predicts 2 types of perceived cognitive impairment (PCI) in multiple sclerosis (MS): general cognitive functioning and executive functioning; and secondarily to assess whether self-efficacy mediates the relationships between depression, fatigue, and PCI. Design Longitudinal analysis of self-report survey data collected over 3 years. Hierarchical regression analyses examined the relationship between self-efficacy and PCI, adjusting for depression and fatigue. Additional analyses tested self-efficacy as a mediator between depression, fatigue, and PCI. Setting Community. Participants Community-dwelling individuals with MS (N=233; age range, 22-83y) were recruited from a larger longitudinal survey study of individuals with MS (N=562). Interventions Not applicable. Main Outcome Measures Primary outcome measures were the Applied Cognition-General Concerns and the Applied Cognition-Executive Function domains of the Quality of Life in Neurological Disorders (NeuroQoL) measures. Results Self-efficacy was significantly correlated with PCI at baseline (r=.40-.53) and 3 years later (r=.36-.44). In multivariate regression analyses, self-efficacy was a significant longitudinal predictor of PCI, both for general cognitive functioning (β=.20, P

Original languageEnglish (US)
Article number56084
Pages (from-to)913-919
Number of pages7
JournalArchives of Physical Medicine and Rehabilitation
Issue number5
StatePublished - May 1 2015
Externally publishedYes



  • Cognition
  • Executive function
  • Longitudinal studies
  • Multiple sclerosis
  • Rehabilitation
  • Self efficacy
  • Self report

ASJC Scopus subject areas

  • Rehabilitation
  • Physical Therapy, Sports Therapy and Rehabilitation

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