Self-assembly of peptides to nanostructures

Dindyal Mandal, Amir Nasrolahi Shirazi, Keykavous Parang

Research output: Contribution to journalArticlepeer-review

Abstract

The formation of well-ordered nanostructures through self-assembly of diverse organic and inorganic building blocks has drawn much attention owing to their potential applications in biology and chemistry. Among all organic building blocks, peptides are one of the most promising platforms due to their biocompatibility, chemical diversity, and resemblance to proteins. Inspired by the protein assembly in biological systems, various self-assembled peptide structures have been constructed using several amino acids and sequences. This review focuses on this emerging area, the recent advances in peptide self-assembly, and formation of different nanostructures, such as tubular structures, fibers, vesicles, and spherical and rod-coil structures. While different peptide nanostructures have been discovered, potential applications are explored in drug delivery, tissue engineering, wound healing, and surfactants. This journal is

Original languageEnglish (US)
Pages (from-to)3544-3561
Number of pages18
JournalOrganic and Biomolecular Chemistry
Volume12
Issue number22
DOIs
StatePublished - Jun 14 2014
Externally publishedYes

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Biochemistry
  • Medicine(all)

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