Selectivity to amyloid- precursor protein cleavage provides hope against Alzheimer's

Taisuke Tomita, Philip C. Wong

Research output: Contribution to journalReview articlepeer-review

Abstract

Toward development of a safe and effective treatment for Alzheimer's disease, Elan Pharmaceuticals reported a novel -secretase inhibitor that specifically targets the cleavage of amyloid- precursor protein, opening the way to design of substrate-specific -secretase inhibitors that would reduce the amyloid burden without significant adverse events.

Original languageEnglish (US)
Article number7
JournalAlzheimer's Research and Therapy
Volume3
Issue number2
DOIs
StatePublished - 2011

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology
  • Cognitive Neuroscience

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