Selection of the optimal lesion site for the relief of parkinsonian tremor on the basis of spectral analysis of neuronal firing patterns

F. A. Lenz, R. R. Tasker, H. C. Kwan, S. Schider, R. Kwong, J. O. Dostrovsky, J. T. Murphy

Research output: Contribution to journalArticlepeer-review

Abstract

Techniques for quantitatively describing the firing properties of neurons have been used to identify thalamic cells with a firing pattern which is correlated with EMG activity during tremor. By locating these cells relative to the anterior border of the somatosensory nucleus and the anterior commissure-posterior commissure line, it may be possible to select the optimal lesion site for the relief of parkinsonian tremor on a rational rather than an empirical basis.

Original languageEnglish (US)
Pages (from-to)338-343
Number of pages6
JournalStereotactic and Functional Neurosurgery
Volume50
Issue number1-6
DOIs
StatePublished - Jan 1 1987
Externally publishedYes

Keywords

  • Parkinson’s disease
  • Spectral analysis
  • Stereotactic surgery
  • Thalamotomy
  • Tremor cell

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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