TY - JOUR
T1 - Selected common diagnostic problems in urologic pathology
T2 - Perspectives from a large consult service in genitourinary pathology
AU - Brimo, Fadi
AU - Epstein, Jonathan I.
PY - 2012/4
Y1 - 2012/4
N2 - Context.-Several common differential diagnoses are encountered in urologic pathology, frequently causing patient referrals for a second opinion. Objectives.-To review 3 common differential diagnoses encountered in a large consultation service in genitourinary pathology, including partial atrophy versus prostatic acinar adenocarcinoma, oncocytoma versus chromophobe renal cell carcinoma, and urothelial carcinoma in situ versus normal urothelium and reactive atypia. We will discuss the detailed, morphologically distinctive features and the usefulness of immunohistochemistry. Data Sources.-Personal experience and review of the current literature. Conclusions.-Careful morphologic assessment and awareness of diagnostic pitfalls are fundamental in reaching a definitive diagnosis in most cases. Immunohistochemistry is useful but should be used only in conjunction with the morphologic impression.
AB - Context.-Several common differential diagnoses are encountered in urologic pathology, frequently causing patient referrals for a second opinion. Objectives.-To review 3 common differential diagnoses encountered in a large consultation service in genitourinary pathology, including partial atrophy versus prostatic acinar adenocarcinoma, oncocytoma versus chromophobe renal cell carcinoma, and urothelial carcinoma in situ versus normal urothelium and reactive atypia. We will discuss the detailed, morphologically distinctive features and the usefulness of immunohistochemistry. Data Sources.-Personal experience and review of the current literature. Conclusions.-Careful morphologic assessment and awareness of diagnostic pitfalls are fundamental in reaching a definitive diagnosis in most cases. Immunohistochemistry is useful but should be used only in conjunction with the morphologic impression.
UR - http://www.scopus.com/inward/record.url?scp=84860012574&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84860012574&partnerID=8YFLogxK
U2 - 10.5858/arpa.2011-0187-RA
DO - 10.5858/arpa.2011-0187-RA
M3 - Article
C2 - 22458899
AN - SCOPUS:84860012574
VL - 136
SP - 360
EP - 371
JO - Archives of Pathology and Laboratory Medicine
JF - Archives of Pathology and Laboratory Medicine
SN - 0003-9985
IS - 4
ER -