Seizures and status epilepticus in the intensive care unit

Research output: Contribution to journalReview articlepeer-review

Abstract

Persistent seizures and failure to regain consciousness following witnessed seizure activity require emergency neurological consultation. Although outcome is largely dependent on underlying cause, early maximal anticonvulsant therapy is critical to reducing morbidity. This review covers important concepts in the clinical and EEG diagnosis of status epilepticus, and discusses treatment algorithms for single and recurrent seizures, emphasizing the need to rationalize therapy depending on the presumed duration of seizure activity. The review takes the perspective of the neurological consultant in the intensive care unit, and considers all pharmacological approaches available to the intensivist as described in the current literature and from clinical experience.

Original languageEnglish (US)
Pages (from-to)668-681
Number of pages14
JournalSeminars in Neurology
Volume28
Issue number5
DOIs
StatePublished - Nov 1 2008

Keywords

  • Intensive care
  • Neurological emergencies
  • Nonconvulsive status epilepticus
  • Refractory status epilepticus
  • Status epilepticus

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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