Seizures and epilepsy: An overview for neuroscientists

Carl E. Stafstrom, Lionel Carmant

Research output: Contribution to journalArticlepeer-review

87 Scopus citations


Epilepsy is one of the most common and disabling neurologic conditions, yet we have an incomplete understanding of the detailed pathophysiology and, thus, treatment rationale for much of epilepsy. This article reviews the clinical aspects of seizures and epilepsy with the goal of providing neuroscientists an introduction to aspects that might be amenable to scientific investigation. Seizures and epilepsy are defined, diagnostic methods are reviewed, various clinical syndromes are discussed, and aspects of differential diagnosis, treatment, and prognosis are considered to enable neuroscientists to formulate basic and translational research questions.

Original languageEnglish (US)
Pages (from-to)1-19
Number of pages19
JournalCold Spring Harbor Perspectives in Biology
Issue number5
StatePublished - 2015

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)


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