Segmentation of the complete superior cerebellar peduncles using a multi-object geometric deformable model

Chuyang Ye, John A. Bogovic, Sarah H. Ying, Jerry L. Prince

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

The superior cerebellar peduncles (SCPs) are white matter tracts that serve as the major efferent pathways from the cerebellum to the thalamus. With diffusion tensor images (DTI), tractography algorithms or volumetric segmentation methods have been able to reconstruct part of the SCPs. However, when the fibers cross, the primary eigenvector (PEV) no longer represents the primary diffusion direction. Therefore, at the crossing of the left and right SCP, known as the decussation of the SCPs (dSCP), fiber tracts propagate incorrectly. To our knowledge, previous methods have not been able to segment the SCPs correctly. In this work, we explore the diffusion properties and seek to volumetrically segment the complete SCPs. The non-crossing SCPs and dSCP are modeled as different objects. A multi-object geometric deformable model is employed to define the boundaries of each piece of the SCPs, with the forces derived from diffusion properties as well as the PEV. We tested our method on a software phantom and real subjects. Results indicate that our method is able to the resolve the crossing and segment the complete SCPs with repeatability.

Original languageEnglish (US)
Title of host publicationISBI 2013 - 2013 IEEE 10th International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro
Pages49-52
Number of pages4
DOIs
StatePublished - Aug 22 2013
Event2013 IEEE 10th International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2013 - San Francisco, CA, United States
Duration: Apr 7 2013Apr 11 2013

Publication series

NameProceedings - International Symposium on Biomedical Imaging
ISSN (Print)1945-7928
ISSN (Electronic)1945-8452

Other

Other2013 IEEE 10th International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2013
CountryUnited States
CitySan Francisco, CA
Period4/7/134/11/13

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Keywords

  • Fiber crossing
  • GGVF
  • MGDM
  • SCP
  • Westin index

ASJC Scopus subject areas

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

Cite this

Ye, C., Bogovic, J. A., Ying, S. H., & Prince, J. L. (2013). Segmentation of the complete superior cerebellar peduncles using a multi-object geometric deformable model. In ISBI 2013 - 2013 IEEE 10th International Symposium on Biomedical Imaging: From Nano to Macro (pp. 49-52). [6556409] (Proceedings - International Symposium on Biomedical Imaging). https://doi.org/10.1109/ISBI.2013.6556409