Sedentary behavior and cardiovascular morbidity and mortality: A science advisory from the American Heart Association

Deborah Rohm Young, Marie France Hivert, Sofiya Alhassan, Sarah M. Camhi, Jane F. Ferguson, Peter T. Katzmarzyk, Cora E. Lewis, Neville Owen, Cynthia K. Perry, Juned Siddique, Celina M. Yong

    Research output: Contribution to journalArticle

    Abstract

    Epidemiological evidence is accumulating that indicates greater time spent in sedentary behavior is associated with all-cause and cardiovascular morbidity and mortality in adults such that some countries have disseminated broad guidelines that recommend minimizing sedentary behaviors. Research examining the possible deleterious consequences of excess sedentary behavior is rapidly evolving, with the epidemiology-based literature ahead of potential biological mechanisms that might explain the observed associations. This American Heart Association science advisory reviews the current evidence on sedentary behavior in terms of assessment methods, population prevalence, determinants, associations with cardiovascular disease incidence and mortality, potential underlying mechanisms, and interventions. Recommendations for future research on this emerging cardiovascular health topic are included. Further evidence is required to better inform public health interventions and future quantitative guidelines on sedentary behavior and cardiovascular health outcomes.

    Original languageEnglish (US)
    Pages (from-to)e262-e279
    JournalCirculation
    Volume134
    Issue number13
    DOIs
    StatePublished - Sep 27 2016

    Keywords

    • AHA Scientific Statements
    • adults
    • cardiovascular disease
    • diabetes mellitus
    • metabolic syndrome
    • mortality
    • prevalence
    • sedentary lifestyle

    ASJC Scopus subject areas

    • Cardiology and Cardiovascular Medicine
    • Physiology (medical)

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    Young, D. R., Hivert, M. F., Alhassan, S., Camhi, S. M., Ferguson, J. F., Katzmarzyk, P. T., Lewis, C. E., Owen, N., Perry, C. K., Siddique, J., & Yong, C. M. (2016). Sedentary behavior and cardiovascular morbidity and mortality: A science advisory from the American Heart Association. Circulation, 134(13), e262-e279. https://doi.org/10.1161/CIR.0000000000000440