Sedation and analgesia to facilitate mechanical ventilation

Michael E. Nemergut, Myron Yaster, Christopher E. Colby

Research output: Contribution to journalReview articlepeer-review

12 Scopus citations


Regardless of age, health care professionals have a professional and ethical obligation to provide safe and effective analgesia to patients undergoing painful procedures. Historically, newborns, particularly premature and sick infants, have been undertreated for pain. Intubation of the trachea and mechanical ventilation are ubiquitous painful procedures in the neonatal intensive care unit that are poorly assessed and treated. The authors review the use of sedation and analgesia to facilitate endotracheal tube placement and mechanical ventilation. Controversies regarding possible adverse neurodevelopmental outcomes after sedative and anesthetic exposure and in the failure to treat pain is also discussed.

Original languageEnglish (US)
Pages (from-to)539-558
Number of pages20
JournalClinics in Perinatology
Issue number3
StatePublished - Sep 2013


  • Analgesia
  • Anesthesia
  • Intubation
  • Mechanical ventilation
  • NICU
  • Sedation

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology


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