Secondary Causes of Myositis

Sarah H. Berth; Thomas E. Lloyd

doi:10.1007/s11940-020-00646-0

Secondary Causes of Myositis

Sarah H. Berth, Thomas E. Lloyd

School of Medicine

Research output: Contribution to journal › Review article › peer-review

Abstract

Purpose of review: The purpose of this paper is to comprehensively evaluate secondary causes of inflammatory myopathies (myositis) and to review treatment options. Recent findings: This review highlights recent advancements in our understanding of known causes of myositis, including newer drugs that may cause myositis such as checkpoint inhibitors and viruses such as influenza, HIV, and SARS-CoV2. We also discuss treatment for malignancy-associated myositis and overlap myositis, thought to be a separate entity from other rheumatologic diseases. Summary: Infections, drugs, rheumatologic diseases, and malignancies are important causes of myositis and are important to diagnose as they may have specific therapies beyond immunomodulatory therapy.

Original language	English (US)
Article number	38
Journal	Current Treatment Options in Neurology
Volume	22
Issue number	11
DOIs	https://doi.org/10.1007/s11940-020-00646-0
State	Published - Nov 1 2020

Keywords

Anti-HMGCR
HIV myositis
Immune checkpoint inhibitors
Immunosuppression
Inflammatory myopathy
Malignancy-associated myositis
Overlap myositis
SARS-CoV-2

ASJC Scopus subject areas

Clinical Neurology

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10.1007/s11940-020-00646-0

Cite this

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title = "Secondary Causes of Myositis",

abstract = "Purpose of review: The purpose of this paper is to comprehensively evaluate secondary causes of inflammatory myopathies (myositis) and to review treatment options. Recent findings: This review highlights recent advancements in our understanding of known causes of myositis, including newer drugs that may cause myositis such as checkpoint inhibitors and viruses such as influenza, HIV, and SARS-CoV2. We also discuss treatment for malignancy-associated myositis and overlap myositis, thought to be a separate entity from other rheumatologic diseases. Summary: Infections, drugs, rheumatologic diseases, and malignancies are important causes of myositis and are important to diagnose as they may have specific therapies beyond immunomodulatory therapy.",

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AU - Lloyd, Thomas E.

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AB - Purpose of review: The purpose of this paper is to comprehensively evaluate secondary causes of inflammatory myopathies (myositis) and to review treatment options. Recent findings: This review highlights recent advancements in our understanding of known causes of myositis, including newer drugs that may cause myositis such as checkpoint inhibitors and viruses such as influenza, HIV, and SARS-CoV2. We also discuss treatment for malignancy-associated myositis and overlap myositis, thought to be a separate entity from other rheumatologic diseases. Summary: Infections, drugs, rheumatologic diseases, and malignancies are important causes of myositis and are important to diagnose as they may have specific therapies beyond immunomodulatory therapy.

KW - Anti-HMGCR

KW - HIV myositis

KW - Immune checkpoint inhibitors

KW - Immunosuppression

KW - Inflammatory myopathy

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KW - Overlap myositis

KW - SARS-CoV-2

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Secondary Causes of Myositis

Abstract

Keywords

ASJC Scopus subject areas

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