TY - JOUR
T1 - Secondary Acquired Cholesteatoma
T2 - Presentation and Tympanoplasty Outcomes
AU - Clark, James H.
AU - Feng, Allen
AU - Harun, Aisha
AU - Brown, Glendine
AU - Francis, Howard W.
N1 - Publisher Copyright:
Copyright © 2016 Otology & Neurotology, Inc.
PY - 2016/8/1
Y1 - 2016/8/1
N2 - Objective: Comparing the clinical features and surgical outcomes of patients undergoing tympanoplasty for secondary acquired cholesteatoma (SAC) versus non-complicated tympanic membrane perforation (TMP). Study Design: Retrospective patient review. Setting: Tertiary-care, academic center. Patients: All 41 patients with diagnosis of SAC confirmed at surgery between January 1, 2007 and June 30, 2014, and an age-matched cohort consisting of patients with TMP. Intervention(s): Tympanoplasty using either medial or lateral graft techniques. Main Outcome Measure(s): Resolution of perforation, SAC, and symptoms. Results: Comparison between the two cohorts failed to reveal significant differences in otologic symptomology, or presentation. There was no significant difference in the resolution of SAC (p = 0.7) between the medial and lateral tympanoplasty techniques. Both techniques also had similar rates of success in the TMP cohort. The medial graft technique was significantly (p = 0.008) more likely to result in a successfully repaired tympanic membrane in the TMP cohort compared with the SAC cohort. The Lateral graft technique demonstrated no significant difference in the likelihood of TMP and SAC resolution. Conclusion: The presentation of SAC is similar to that of TMP despite being a separate clinical entity. A clinician's ability to distinguish the two is important to mitigate the destructive potential of untreated SAC and correctly council patients on tympanoplasty success rates. This study was unable to demonstrate a significant difference in disease control between the medial and lateral tympanoplasty techniques, although potential advantages of each technique are discussed.
AB - Objective: Comparing the clinical features and surgical outcomes of patients undergoing tympanoplasty for secondary acquired cholesteatoma (SAC) versus non-complicated tympanic membrane perforation (TMP). Study Design: Retrospective patient review. Setting: Tertiary-care, academic center. Patients: All 41 patients with diagnosis of SAC confirmed at surgery between January 1, 2007 and June 30, 2014, and an age-matched cohort consisting of patients with TMP. Intervention(s): Tympanoplasty using either medial or lateral graft techniques. Main Outcome Measure(s): Resolution of perforation, SAC, and symptoms. Results: Comparison between the two cohorts failed to reveal significant differences in otologic symptomology, or presentation. There was no significant difference in the resolution of SAC (p = 0.7) between the medial and lateral tympanoplasty techniques. Both techniques also had similar rates of success in the TMP cohort. The medial graft technique was significantly (p = 0.008) more likely to result in a successfully repaired tympanic membrane in the TMP cohort compared with the SAC cohort. The Lateral graft technique demonstrated no significant difference in the likelihood of TMP and SAC resolution. Conclusion: The presentation of SAC is similar to that of TMP despite being a separate clinical entity. A clinician's ability to distinguish the two is important to mitigate the destructive potential of untreated SAC and correctly council patients on tympanoplasty success rates. This study was unable to demonstrate a significant difference in disease control between the medial and lateral tympanoplasty techniques, although potential advantages of each technique are discussed.
KW - Lateral graft tympanoplasty
KW - Medial graft tympanoplasty
KW - Secondary acquired cholesteatoma
KW - Tympanoplasty
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U2 - 10.1097/MAO.0000000000001100
DO - 10.1097/MAO.0000000000001100
M3 - Article
C2 - 27273390
AN - SCOPUS:84973325982
SN - 1531-7129
VL - 37
SP - 902
EP - 907
JO - Otology and Neurotology
JF - Otology and Neurotology
IS - 7
ER -