Search for evidence of herpes simplex virus, type 1, or varicella‐zoster virus infection in postmortem brain tissue from schizophrenic patients

R. C. Alexander, G. Cabirac, T. Lowenkopf, M. Casanova, J. Kleinman, R. J. Wyatt, D. G. Kirch

Research output: Contribution to journalArticlepeer-review

Abstract

The highly sensitive polymerase chain reaction (PCR) was used to search for herpes simplex virus type 1 (HSV‐I) or varicella‐zoster virus (VZV) in the DNA extracted from postmortem temporal cortex samples of 8 schizophrenic subjects, 8 nonschizophrenic suicide victims and 8 normal controls. HSV‐I or VZV‐specific DNA amplification was not detected in any of the samples studied.

Original languageEnglish (US)
Pages (from-to)418-420
Number of pages3
JournalActa Psychiatrica Scandinavica
Volume86
Issue number5
DOIs
StatePublished - Nov 1992
Externally publishedYes

Keywords

  • herpes simplex virus
  • polymerase chain reaction
  • schizophrenia
  • varicella‐zoster virus

ASJC Scopus subject areas

  • Psychiatry and Mental health

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