Screening for Pancreatic Cancer

Research output: Contribution to journalReview article

Abstract

Pancreatic cancer (PC) is a highly fatal disease that can only be cured by complete surgical resection. However, most patients with PC have unresectable disease at the time of diagnosis, highlighting the need to detect PC and its precursor lesions earlier in asymptomatic patients. Screening is not cost-effective for population-based screening of PC. Individuals with genetic risk factors for PC based on family history or known PC-associated genetic syndromes, however, can be a potential target for PC screening programs. This article provides an overview of the epidemiology and genetic background of familial PC and discusses diagnostic and management approaches.

Original languageEnglish (US)
Pages (from-to)1223-1233
Number of pages11
JournalSurgical Clinics of North America
Volume96
Issue number6
DOIs
Publication statusPublished - Dec 1 2016

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Keywords

  • Familial pancreatic cancer
  • Intraductal papillary mucinous neoplasm
  • Pancreatic cancer
  • Pancreatic cyst
  • Pancreatic intraepithelial neoplasia
  • Screening

ASJC Scopus subject areas

  • Surgery
  • Medicine(all)

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