Screening for Narrow Angles in the Singapore Population

Evaluation of New Noncontact Screening Methods

Raghavan Lavanya, Paul J. Foster, Lisandro M. Sakata, David S Friedman, Kenji Kashiwagi, Tien Yin Wong, Han T. Aung, Tamuno Alfred, Hong Gao, Adrian G. Ee, Steve K. Seah, Tin Aung

Research output: Contribution to journalArticle

Abstract

Purpose: To assess the screening effectiveness of 3 new noncontact devices, the scanning peripheral anterior chamber depth analyzer (SPAC) (Takagi, Nagano, Japan), which measures peripheral anterior chamber depth (ACD); IOLMaster (Carl Zeiss Meditec, Jena, Germany), which measures central ACD; and Visante anterior segment optical coherence tomography (AS-OCT) (Visante, Carl Zeiss Meditec, Dublin, CA), which images the angles, and to compare these instruments with gonioscopy in identifying people with narrow angles (NAs). Design: Cross-sectional, observational, community-based study. Participants: Phakic subjects aged ≥50 years without ophthalmic symptoms who were recruited from a community polyclinic in Singapore. Methods: All subjects underwent examination with SPAC, IOLMaster, and AS-OCT in the dark by a single operator. Gonioscopy was performed by an ophthalmologist masked to the instruments' findings. The area under the curve (AUC) receiver operating characteristic (ROC) was generated to assess the performance of these tests in detecting people with a NA in either eye. Main Outcome Measures: Eyes were classified as having NAs by gonioscopy if the posterior pigmented trabecular meshwork could be seen for ≤2 quadrants of the angle circumference with or without peripheral anterior synechiae. Results: A total of 2052 subjects were examined and underwent all 3 tests. The prevalence of a NA in at least 1 eye diagnosed by gonioscopy was 20.4% (422 subjects). The AUC for the SPAC using a numeric grade

Original languageEnglish (US)
JournalOphthalmology
Volume115
Issue number10
DOIs
StatePublished - Oct 2008

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Gonioscopy
Singapore
Anterior Chamber
Population
Optical Coherence Tomography
Area Under Curve
Trabecular Meshwork
ROC Curve
Germany
Japan
Outcome Assessment (Health Care)
Equipment and Supplies

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Screening for Narrow Angles in the Singapore Population : Evaluation of New Noncontact Screening Methods. / Lavanya, Raghavan; Foster, Paul J.; Sakata, Lisandro M.; Friedman, David S; Kashiwagi, Kenji; Wong, Tien Yin; Aung, Han T.; Alfred, Tamuno; Gao, Hong; Ee, Adrian G.; Seah, Steve K.; Aung, Tin.

In: Ophthalmology, Vol. 115, No. 10, 10.2008.

Research output: Contribution to journalArticle

Lavanya, R, Foster, PJ, Sakata, LM, Friedman, DS, Kashiwagi, K, Wong, TY, Aung, HT, Alfred, T, Gao, H, Ee, AG, Seah, SK & Aung, T 2008, 'Screening for Narrow Angles in the Singapore Population: Evaluation of New Noncontact Screening Methods', Ophthalmology, vol. 115, no. 10. https://doi.org/10.1016/j.ophtha.2008.03.015
Lavanya, Raghavan ; Foster, Paul J. ; Sakata, Lisandro M. ; Friedman, David S ; Kashiwagi, Kenji ; Wong, Tien Yin ; Aung, Han T. ; Alfred, Tamuno ; Gao, Hong ; Ee, Adrian G. ; Seah, Steve K. ; Aung, Tin. / Screening for Narrow Angles in the Singapore Population : Evaluation of New Noncontact Screening Methods. In: Ophthalmology. 2008 ; Vol. 115, No. 10.
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AU - Aung, Han T.

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