Screening for DSM-IV-TR cognitive disorder NOS in Parkinson's disease using the Mattis Dementia Rating Scale

Gregory M. Pontone, Justin Palanci, James R. Williams, Susan Spear Bassett

Research output: Contribution to journalArticle


Objective This study explores the utility of the Mattis Dementia Rating Scale (MDRS) as a screening tool for the Diagnostic and Statistical Manual for Mental Disorders 4th edition (DSM-IV-TR) diagnosis cognitive disorder not otherwise specified (NOS) in Parkinson's disease (PD). Methods A total of 125 individuals with PD were diagnosed using DSM-IV-TR criteria for cognitive disorder NOS and dementia. Receiver operating characteristics (ROC) tested the discriminant validity of the MDRS, with the clinician's diagnosis serving as the gold standard. Results The MDRS ROC curve to discriminate subjects with cognitive disorder NOS from non-demented subjects had an area under the curve of 0.59 (standard error = 0.08, 95% CI: 0.43-0.74). Conclusions The MDRS is not effective for identifying PD patients with cognitive disorder NOS without dementia.

Original languageEnglish (US)
Pages (from-to)364-371
Number of pages8
JournalInternational journal of geriatric psychiatry
Issue number4
StatePublished - Apr 1 2013



  • Dementia Rating Scale
  • Parkinson's disease
  • cognitive impairment
  • cognitive screening
  • non-motor symptoms

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Psychiatry and Mental health

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