Scrambler therapy for treatment-resistant central neuropathic pain in a patient with transverse myelitis

Maureen A. Mealy, Scott D. Newsome, Sharon L. Kozachik, Michael Levy, Thomas J. Smith

Research output: Contribution to journalArticle

Abstract

Central neuropathic pain is a severely disabling consequence of conditions that cause tissue damage in the central nervous system. It is often refractory to treatments commonly used for peripheral neuropathy. Scrambler therapy is an emerging noninvasive pain-modifying technique that uses transcutaneous electrical stimulation of nociceptive fibers with the intent of reorganizing maladaptive signaling pathways. It has been examined for the treatment of peripheral neuropathy with favorable safety and efficacy outcomes, but its application to central neuropathic pain has not been reported in transverse myelitis. We describe the use of Scrambler therapy in a patient with persistent central neuropathic pain due to transverse myelitis. The patient had tried multiple drugs for treatment of the pain, but they were not effective or caused adverse effects. After a course of Scrambler therapy, pain scores improved considerably more than what was reported with previous pharmacologic and nonpharmacologic interventions. This case supports further investigation of Scrambler therapy in multiple sclerosis, neuromyelitis optica spectrum disorder, and other immune-mediated disorders that damage the central nervous system.

Original languageEnglish (US)
Pages (from-to)76-80
Number of pages5
JournalInternational Journal of MS Care
Volume21
Issue number2
DOIs
StatePublished - Mar 1 2019

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Transverse Myelitis
Neuralgia
Peripheral Nervous System Diseases
Pain
Therapeutics
Central Nervous System
Neuromyelitis Optica
Transcutaneous Electric Nerve Stimulation
Immune System Diseases
Multiple Sclerosis
Safety

ASJC Scopus subject areas

  • Clinical Neurology
  • Advanced and Specialized Nursing

Cite this

Scrambler therapy for treatment-resistant central neuropathic pain in a patient with transverse myelitis. / Mealy, Maureen A.; Newsome, Scott D.; Kozachik, Sharon L.; Levy, Michael; Smith, Thomas J.

In: International Journal of MS Care, Vol. 21, No. 2, 01.03.2019, p. 76-80.

Research output: Contribution to journalArticle

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