Sclerouveitis associated with rosai-dorfman disease in an HIV-infected patient

Anne K. Monroe; Bryn M. Burkholder; Nicholas J. Butler; Amy S. Duffield

doi:10.3109/09273948.2013.767914

Sclerouveitis associated with rosai-dorfman disease in an HIV-infected patient

Anne K. Monroe, Bryn M. Burkholder, Nicholas J. Butler, Amy S. Duffield

School of Medicine

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

Purpose: To describe a case of Rosai-Dorfman-associated sclerouveitis in an HIV-infected patient. Design: Case report. Methods: A 49-year-old man with HIV had bilateral eye pain, redness, photophobia, and multiple systemic complaints. He underwent serial ocular examinations, abdomen/pelvis CT scan, and lymph node biopsy. Results: Ophthalmologic evaluation revealed bilateral, nongranulomatous anterior uveitis and anterior scleritis. Biopsy of a retroperitoneal lymph node identified on CT revealed mixed inflammatory infiltrate composed of histiocytes, lymphocytes, and plasma cells involving fibroadipose tissue, indicating Rosai-Dorfman disease. Conclusions: This is the first report of sclerouveitis in Rosai-Dorfman disease. Rosai-Dorfman is typically self-limiting, occurring rarely in HIV.

Original language	English (US)
Pages (from-to)	236-238
Number of pages	3
Journal	Ocular Immunology and Inflammation
Volume	22
Issue number	3
DOIs	https://doi.org/10.3109/09273948.2013.767914
State	Published - Jun 2014

Keywords

Corticosteroids
Emperipolesis
HIV
Rosai-Dorfman
Sclerouveitis

ASJC Scopus subject areas

Immunology and Allergy
Ophthalmology

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10.3109/09273948.2013.767914

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title = "Sclerouveitis associated with rosai-dorfman disease in an HIV-infected patient",

abstract = "Purpose: To describe a case of Rosai-Dorfman-associated sclerouveitis in an HIV-infected patient. Design: Case report. Methods: A 49-year-old man with HIV had bilateral eye pain, redness, photophobia, and multiple systemic complaints. He underwent serial ocular examinations, abdomen/pelvis CT scan, and lymph node biopsy. Results: Ophthalmologic evaluation revealed bilateral, nongranulomatous anterior uveitis and anterior scleritis. Biopsy of a retroperitoneal lymph node identified on CT revealed mixed inflammatory infiltrate composed of histiocytes, lymphocytes, and plasma cells involving fibroadipose tissue, indicating Rosai-Dorfman disease. Conclusions: This is the first report of sclerouveitis in Rosai-Dorfman disease. Rosai-Dorfman is typically self-limiting, occurring rarely in HIV.",

keywords = "Corticosteroids, Emperipolesis, HIV, Rosai-Dorfman, Sclerouveitis",

author = "Monroe, {Anne K.} and Burkholder, {Bryn M.} and Butler, {Nicholas J.} and Duffield, {Amy S.}",

year = "2014",

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AU - Monroe, Anne K.

AU - Burkholder, Bryn M.

AU - Butler, Nicholas J.

AU - Duffield, Amy S.

PY - 2014/6

Y1 - 2014/6

N2 - Purpose: To describe a case of Rosai-Dorfman-associated sclerouveitis in an HIV-infected patient. Design: Case report. Methods: A 49-year-old man with HIV had bilateral eye pain, redness, photophobia, and multiple systemic complaints. He underwent serial ocular examinations, abdomen/pelvis CT scan, and lymph node biopsy. Results: Ophthalmologic evaluation revealed bilateral, nongranulomatous anterior uveitis and anterior scleritis. Biopsy of a retroperitoneal lymph node identified on CT revealed mixed inflammatory infiltrate composed of histiocytes, lymphocytes, and plasma cells involving fibroadipose tissue, indicating Rosai-Dorfman disease. Conclusions: This is the first report of sclerouveitis in Rosai-Dorfman disease. Rosai-Dorfman is typically self-limiting, occurring rarely in HIV.

AB - Purpose: To describe a case of Rosai-Dorfman-associated sclerouveitis in an HIV-infected patient. Design: Case report. Methods: A 49-year-old man with HIV had bilateral eye pain, redness, photophobia, and multiple systemic complaints. He underwent serial ocular examinations, abdomen/pelvis CT scan, and lymph node biopsy. Results: Ophthalmologic evaluation revealed bilateral, nongranulomatous anterior uveitis and anterior scleritis. Biopsy of a retroperitoneal lymph node identified on CT revealed mixed inflammatory infiltrate composed of histiocytes, lymphocytes, and plasma cells involving fibroadipose tissue, indicating Rosai-Dorfman disease. Conclusions: This is the first report of sclerouveitis in Rosai-Dorfman disease. Rosai-Dorfman is typically self-limiting, occurring rarely in HIV.

KW - Corticosteroids

KW - Emperipolesis

KW - HIV

KW - Rosai-Dorfman

KW - Sclerouveitis

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Sclerouveitis associated with rosai-dorfman disease in an HIV-infected patient

Abstract

Keywords

ASJC Scopus subject areas

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