Sclerouveitis associated with rosai-dorfman disease in an HIV-infected patient

Anne K. Monroe, Bryn M. Burkholder, Nicholas J. Butler, Amy S. Duffield

Research output: Contribution to journalArticle

Abstract

Purpose: To describe a case of Rosai-Dorfman-associated sclerouveitis in an HIV-infected patient. Design: Case report. Methods: A 49-year-old man with HIV had bilateral eye pain, redness, photophobia, and multiple systemic complaints. He underwent serial ocular examinations, abdomen/pelvis CT scan, and lymph node biopsy. Results: Ophthalmologic evaluation revealed bilateral, nongranulomatous anterior uveitis and anterior scleritis. Biopsy of a retroperitoneal lymph node identified on CT revealed mixed inflammatory infiltrate composed of histiocytes, lymphocytes, and plasma cells involving fibroadipose tissue, indicating Rosai-Dorfman disease. Conclusions: This is the first report of sclerouveitis in Rosai-Dorfman disease. Rosai-Dorfman is typically self-limiting, occurring rarely in HIV.

Original languageEnglish (US)
Pages (from-to)236-238
Number of pages3
JournalOcular Immunology and Inflammation
Volume22
Issue number3
DOIs
StatePublished - Jun 2014

Keywords

  • Corticosteroids
  • Emperipolesis
  • HIV
  • Rosai-Dorfman
  • Sclerouveitis

ASJC Scopus subject areas

  • Immunology and Allergy
  • Ophthalmology

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