Scleroderma and microangiopathic hemolytic anemia

W. R. Salyer, D. C. Salyer, R. H. Heptinstall

Research output: Contribution to journalArticlepeer-review


Microangiopathic hemolytic anemia was found in 7 of 20 patients with systemic scleroderma, an indication that this complication is not uncommon. Since only 4 had severe hypertension, pressures in the 'malignant' range seem not to be necessary for the development of the anemia. All 7 patients had renal arterial fibrin deposits, which supports the concept that erythrocyte fragmentation results from contact with intravascular fibrin.

Original languageEnglish (US)
Pages (from-to)895-897
Number of pages3
JournalAnnals of internal medicine
Issue number6
StatePublished - Jan 1 1973

ASJC Scopus subject areas

  • Internal Medicine


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