Microangiopathic hemolytic anemia was found in 7 of 20 patients with systemic scleroderma, an indication that this complication is not uncommon. Since only 4 had severe hypertension, pressures in the 'malignant' range seem not to be necessary for the development of the anemia. All 7 patients had renal arterial fibrin deposits, which supports the concept that erythrocyte fragmentation results from contact with intravascular fibrin.
ASJC Scopus subject areas
- Internal Medicine