Scleritis and Peripheral Ulcerative Keratitis

Anat Galor, Jennifer E. Thorne

Research output: Contribution to journalReview articlepeer-review


Scleritis and peripheral ulcerative keratitis (PUK) can present as isolated conditions or as part of a systemic inflammatory or infectious disorder. Both are serious ocular conditions that can result in vision loss and require early diagnosis and treatment. Nearly two thirds of patients with non-infectious scleritis require systemic glucocorticoid therapy and one fourth need a glucocorticoid-sparing agent as well. Essentially all patients with non-infectious PUK require systemic glucocorticoids. A detailed clinical history, thorough physical examination, and thoughtful laboratory evaluations are important in the exclusion of underlying disorders and extraocular involvement.

Original languageEnglish (US)
Pages (from-to)835-854
Number of pages20
JournalRheumatic Disease Clinics of North America
Issue number4
StatePublished - Nov 2007

ASJC Scopus subject areas

  • Rheumatology


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