Scintigraphic detection of pulmonary embolism in patients with obstructive pulmonary disease

P. O. Alderson, D. R. Biello, K. G. Sacchariah, B. A. Siegel

Research output: Contribution to journalArticle

Abstract

The 133Xe ventilation (V) studies, 99mTc perfusion (P) lung images, and pulmonary angiograms of 83 patients with obstructive pulmonary disease (OPD) and suspected pulmonary emboli (PE) were reviewed. Each patient had ventilation abnormalities suggesting OPD and at least one region showing matched V-P abnormalities. All angiograms were obtained within 72 hours of the V-P study and were reviewed independently. The overall sensitivity of V-P imaging for PE in this population was 0.83 and its specificity was 0.92. False-negative interpretations occurred in three of the 16 patients who showed ventilation abnormalities in more than 50% of their lung fields. In the 67 patients with ventilation abnormalities in ≤50% of their lung fields the sensitivity (0.95) and specificity (0.94) for detecting PE were high. V-P imaging is a reliable method for detecting PE in patients with regions of V-P match, if the ventilation abnormalities are limited in extent.

Original languageEnglish (US)
Pages (from-to)661-666
Number of pages6
JournalRadiology
Volume138
Issue number5
StatePublished - 1981

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Obstructive Lung Diseases
Pulmonary Embolism
Lung
Ventilation
Embolism
Angiography
Perfusion
Sensitivity and Specificity

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Alderson, P. O., Biello, D. R., Sacchariah, K. G., & Siegel, B. A. (1981). Scintigraphic detection of pulmonary embolism in patients with obstructive pulmonary disease. Radiology, 138(5), 661-666.

Scintigraphic detection of pulmonary embolism in patients with obstructive pulmonary disease. / Alderson, P. O.; Biello, D. R.; Sacchariah, K. G.; Siegel, B. A.

In: Radiology, Vol. 138, No. 5, 1981, p. 661-666.

Research output: Contribution to journalArticle

Alderson, PO, Biello, DR, Sacchariah, KG & Siegel, BA 1981, 'Scintigraphic detection of pulmonary embolism in patients with obstructive pulmonary disease', Radiology, vol. 138, no. 5, pp. 661-666.
Alderson PO, Biello DR, Sacchariah KG, Siegel BA. Scintigraphic detection of pulmonary embolism in patients with obstructive pulmonary disease. Radiology. 1981;138(5):661-666.
Alderson, P. O. ; Biello, D. R. ; Sacchariah, K. G. ; Siegel, B. A. / Scintigraphic detection of pulmonary embolism in patients with obstructive pulmonary disease. In: Radiology. 1981 ; Vol. 138, No. 5. pp. 661-666.
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